HitPredict

Interactor 1: PRC2A (P48634)
Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2)
Gene: PRRC2A

Interactor 2: RC3H2 (Q9HBD1)
Roquin-2 (EC 2.3.2.27) (Membrane-associated nucleic acid-binding protein) (RING finger and CCCH-type zinc finger domain-containing protein 2) (RING finger protein 164) (RING-type E3 ubiquitin transferase Roquin-2)
Gene: RC3H2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30209976, 29395067
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2157 Hs			1 1191
+	Hs
		1127701 PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		820945 PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		807847 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		1219851 ANKH1_HUMAN (88-992): 9.48e-35: 148: 14.15		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		1127618 PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1136160 ANKH1_HUMAN (88-992): 9.48e-35: 148: 14.15		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		1136360 SRRM2_HUMAN (238-2035): 2.29e-34: 147: 9.83		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		257584 PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00		ANR17_HUMAN (335-957): 1.44e-12: 74.7: 8.44
+	Hs
		257620 PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60		ANR17_HUMAN (335-957): 1.44e-12: 74.7: 8.44
+	Hs
		1127685 PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60		CECR2_HUMAN (356-1006): 5.51e-09: 62.7: 8.82
+	Hs
		554259 MUC1_HUMAN (1123-2148): 1.84e-48: 193: 12.03		MUC1_HUMAN (344-901): 6.29e-21: 102: 9.70
+	Hs
		257652 ANKH1_HUMAN (88-992): 9.48e-35: 148: 14.15		ANR17_HUMAN (335-957): 1.44e-12: 74.7: 8.44
+	Hs
		325654 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		LATS1_HUMAN (518-1066): 1.1e-09: 65: 11.05
+	Hs
		807652 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		SC24C_HUMAN (362-642): 1.58e-09: 64.6: 12.98
+	Hs
		807791 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		CBP_HUMAN (556-893): 1.74e-09: 64.6: 9.77
+	Hs
		807793 MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83		PRG4_HUMAN (469-824): 3.07e-09: 63.7: 13.04
+	Hs
		325944 SRRM2_HUMAN (238-2035): 2.29e-34: 147: 9.83		LATS1_HUMAN (518-1066): 1.1e-09: 65: 11.05
+	Hs
		311825 TACC2_HUMAN (38-2028): 6.76e-31: 136: 8.37		CBP_HUMAN (556-893): 1.74e-09: 64.6: 9.77
+	Hs
		325703 ZO1_HUMAN (265-982): 3.45e-30: 133: 13.23		LATS1_HUMAN (518-1066): 1.1e-09: 65: 11.05
+	Hs
		1270850 NCOR2_HUMAN (550-2096): 1.47e-20: 102: 10.40		CBP_HUMAN (556-893): 1.74e-09: 64.6: 9.77