HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: ERCC8 (Q13216)
DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA)
Gene: ERCC8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	29531219, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 396
+	Hs
		821387 TCPE_HUMAN (1-541): 0: 635: 100.00		TBL1Y_HUMAN (2-321): 1.67e-67: 224: 18.24
+	Hs
		826641 TCPG_HUMAN (14-540): 0: 572: 33.15		ERCC8_HUMAN (1-396): 7.48e-87: 270: 100.00
+	Hs
		821355 TCPE_HUMAN (1-541): 0: 635: 100.00		SNR40_HUMAN (140-394): 5.23e-55: 186: 13.41
+	Hs
		821152 TCPE_HUMAN (1-541): 0: 635: 100.00		WDR5_HUMAN (218-396): 2.25e-46: 163: 20.44
+	Hs
		821326 TCPE_HUMAN (1-541): 0: 635: 100.00		POC1B_HUMAN (228-395): 1.45e-33: 132: 15.29
+	Hs
		821316 TCPE_HUMAN (1-541): 0: 635: 100.00		POC1A_HUMAN (4-130): 3.18e-24: 105: 13.38
+	Hs
		826601 TCPG_HUMAN (14-540): 0: 572: 33.15		WDR5_HUMAN (218-396): 2.25e-46: 163: 20.44
+	Hs
		826748 TCPG_HUMAN (14-540): 0: 572: 33.15		WDR5B_HUMAN (220-396): 1.61e-42: 153: 18.99
+	Hs
		792942 TCPG_HUMAN (14-540): 0: 572: 33.15		LIS1_HUMAN (218-395): 1.1e-38: 145: 14.44
+	Hs
		821437 TCPE_HUMAN (1-541): 0: 635: 100.00		NLE1_HUMAN (3-71): 4.91e-16: 81.3: 18.57
+	Hs
		821227 TCPE_HUMAN (1-541): 0: 635: 100.00		RBBP7_HUMAN (129-368): 4.26e-15: 78.3: 19.22
+	Hs
		826784 TCPG_HUMAN (14-540): 0: 572: 33.15		POC1B_HUMAN (228-395): 1.45e-33: 132: 15.29
+	Hs
		821443 TCPE_HUMAN (1-541): 0: 635: 100.00		WSB2_HUMAN (98-272): 5.13e-11: 65.9: 28.81
+	Hs
		821182 TCPE_HUMAN (1-541): 0: 635: 100.00		CDC20_HUMAN (69-352): 8.11e-11: 65.5: 23.81
+	Hs
		196971 TCPE_HUMAN (1-541): 0: 635: 100.00		PRP4_HUMAN (89-272): 1.17e-10: 65.1: 26.27
+	Hs
		826772 TCPG_HUMAN (14-540): 0: 572: 33.15		POC1A_HUMAN (4-130): 3.18e-24: 105: 13.38
+	At
		138361 TCPE_ARATH (6-538): 0: 606: 68.29		PEX7_ARATH (98-229): 1.28e-11: 67: 32.33
+	Ce
		812723 TCPE_CAEEL (3-540): 0: 586: 68.40		LIN53_CAEEL (98-276): 1.11e-09: 61.6: 25.82
+	Hs
		826632 TCPG_HUMAN (14-540): 0: 572: 33.15		CDC20_HUMAN (69-352): 8.11e-11: 65.5: 23.81
+	Hs
		196973 TCPG_HUMAN (14-540): 0: 572: 33.15		PRP4_HUMAN (89-272): 1.17e-10: 65.1: 26.27