HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: SKI8 (Q9GZS3)
Superkiller complex protein 8 (Ski8) (Meiotic recombination REC14 protein homolog) (WD repeat-containing protein 61) [Cleaved into: Superkiller complex protein 8, N-terminally processed (WD repeat-containing protein 61, N-terminally processed)]
Gene: SKIC8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 305
+	Hs
		821437 TCPE_HUMAN (1-541): 0: 635: 100.00		NLE1_HUMAN (7-304): 9.15e-91: 279: 21.61
+	Hs
		826875 TCPG_HUMAN (14-540): 0: 572: 33.15		SKI8_HUMAN (1-305): 2.86e-101: 300: 100.00
+	Hs
		792942 TCPG_HUMAN (14-540): 0: 572: 33.15		LIS1_HUMAN (2-262): 1.96e-85: 263: 20.64
+	Hs
		821355 TCPE_HUMAN (1-541): 0: 635: 100.00		SNR40_HUMAN (2-216): 4.5e-59: 194: 22.42
+	Hs
		826807 TCPG_HUMAN (14-540): 0: 572: 33.15		FBXW7_HUMAN (91-303): 1.6e-63: 214: 24.30
+	Hs
		821152 TCPE_HUMAN (1-541): 0: 635: 100.00		WDR5_HUMAN (179-304): 4.63e-41: 147: 33.33
+	Hs
		821316 TCPE_HUMAN (1-541): 0: 635: 100.00		POC1A_HUMAN (2-133): 1.24e-33: 128: 20.46
+	Hs
		821392 TCPE_HUMAN (1-541): 0: 635: 100.00		KTNB1_HUMAN (177-304): 1.18e-32: 128: 24.03
+	Hs
		821326 TCPE_HUMAN (1-541): 0: 635: 100.00		POC1B_HUMAN (2-94): 2.03e-19: 90: 21.51
+	Hs
		826601 TCPG_HUMAN (14-540): 0: 572: 33.15		WDR5_HUMAN (179-304): 4.63e-41: 147: 33.33
+	Hs
		903467 TCPH_HUMAN (12-539): 0: 570: 29.64		WDR5_HUMAN (179-304): 4.63e-41: 147: 33.33
+	Hs
		196971 TCPE_HUMAN (1-541): 0: 635: 100.00		PRP4_HUMAN (218-304): 3.86e-14: 74.2: 13.68
+	Hs
		826748 TCPG_HUMAN (14-540): 0: 572: 33.15		WDR5B_HUMAN (179-304): 1.89e-37: 137: 30.95
+	Hs
		1202777 TCPH_HUMAN (12-539): 0: 570: 29.64		WDR5B_HUMAN (179-304): 1.89e-37: 137: 30.95
+	Hs
		826772 TCPG_HUMAN (14-540): 0: 572: 33.15		POC1A_HUMAN (2-133): 1.24e-33: 128: 20.46
+	Hs
		1240450 TCPH_HUMAN (12-539): 0: 570: 29.64		POC1A_HUMAN (2-133): 1.24e-33: 128: 20.46
+	Hs
		1306654 TCPH_HUMAN (12-539): 0: 570: 29.64		KTNB1_HUMAN (177-304): 1.18e-32: 128: 24.03
+	Hs
		826784 TCPG_HUMAN (14-540): 0: 572: 33.15		POC1B_HUMAN (2-94): 2.03e-19: 90: 21.51
+	Hs
		196973 TCPG_HUMAN (14-540): 0: 572: 33.15		PRP4_HUMAN (218-304): 3.86e-14: 74.2: 13.68
+	Hs
		197078 TCPH_HUMAN (12-539): 0: 570: 29.64		PRP4_HUMAN (218-304): 3.86e-14: 74.2: 13.68