Protein: TCPW
T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (CCT-zeta-like) (Chaperonin containing T-complex polypeptide 1 subunit 6B) (TCP-1-zeta-like) (Testis-specific Tcp20) (Testis-specific protein TSA303)

Gene: TCPW, CCT6B
Organism: Homo sapiens
Interactions: 187
UniProt ID: Q92526

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0005832 - chaperonin-containing T-complex
GO:0006457 - protein folding
GO:0016887 - ATP hydrolysis activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

142383

PEX7
Peroxisomal targeting signal 2 receptor

3

20

High-throughput

0.861

High

945584

FBXW4
F-box/WD repeat-containing protein 4

3

20

High-throughput

0.861

High

1338873

NUP43
Nucleoporin Nup43

3

20

High-throughput

0.861

High

1363689

LST8
Target of rapamycin complex subunit LST8

3

20

High-throughput

0.861

High

1327572

WDTC1
WD and tetratricopeptide repeats protein 1

3

20

High-throughput

0.855

High

224332

BUB3
Mitotic checkpoint protein BUB3

2

20

High-throughput

0.811

High

882066

TCPG
T-complex protein 1 subunit gamma

2

19

High-throughput

0.811

High

964691

DCAF7
DDB1- and CUL4-associated factor 7

2

20

High-throughput

0.811

High

1201014

ACTBL
Beta-actin-like protein 2

2

20

High-throughput

0.811

High

1215336

DCAF8
DDB1- and CUL4-associated factor 8

2

20

High-throughput

0.811

High

1340765

COP1
E3 ubiquitin-protein ligase COP1

2

20

High-throughput

0.811

High

1363669

DC2I2
Cytoplasmic dynein 2 intermediate chain 2

2

20

High-throughput

0.811

High

1363680

MEP50
Methylosome protein WDR77

2

20

High-throughput

0.811

High

1363708

TBG2
Tubulin gamma-2 chain

2

20

High-throughput

0.811

High

1363684

WDR83
WD repeat domain-containing protein 83

4

20

High-throughput

0.797

High

837244

ACTY
Beta-centractin

2

20

High-throughput

0.789

High

355260

ACL6A
Actin-like protein 6A

3

20

High-throughput

0.770

High

1118539

TBB2A
Tubulin beta-2A chain

3

20

High-throughput

0.770

High

1200053

EIPR1
EARP and GARP complex-interacting protein 1

3

20

High-throughput

0.770

High

1363673

DCAF5
DDB1- and CUL4-associated factor 5

3

20

High-throughput

0.770

High

1363707

SC31B
Protein transport protein Sec31B

3

20

High-throughput

0.770

High

821483

TCPZ
T-complex protein 1 subunit zeta

2

17

High-throughput

0.754

High

1259390

TBA1A
Tubulin alpha-1A chain

2

20

High-throughput

0.754

High

996791

TBA1B
Tubulin alpha-1B chain

2

20

High-throughput

0.726

High

1287301

WDR86
WD repeat-containing protein 86

2

20

High-throughput

0.726

High

1352248

DCA11
DDB1- and CUL4-associated factor 11

2

20

High-throughput

0.726

High

1363679

TBL1Y
F-box-like/WD repeat-containing protein TBL1Y

2

20

High-throughput

0.726

High

1363681

TBA1C
Tubulin alpha-1C chain

2

20

High-throughput

0.726

High

1363692

DNAI2
Dynein axonemal intermediate chain 2

2

20

High-throughput

0.726

High

65590

TBAL3
Tubulin alpha chain-like 3

2

20

High-throughput

0.705

High

408118

TBB4A
Tubulin beta-4A chain

1

20

High-throughput

0.691

High

876093

TCPE
T-complex protein 1 subunit epsilon

1

19

High-throughput

0.691

High

958480

ACTZ
Alpha-centractin

1

20

High-throughput

0.691

High

997062

TBA4A
Tubulin alpha-4A chain

1

20

High-throughput

0.691

High

1007175

TCPB
T-complex protein 1 subunit beta

1

20

High-throughput

0.691

High

1220953

FBXW9
F-box/WD repeat-containing protein 9

1

20

High-throughput

0.691

High

1363665

FBXW5
F-box/WD repeat-containing protein 5

1

5

High-throughput

0.691

High

1363678

TCPH
T-complex protein 1 subunit eta

1

20

High-throughput

0.691

High

1363687

TCAB1
Telomerase Cajal body protein 1

1

20

High-throughput

0.691

High

1363693

SKI8
Superkiller complex protein 8

1

20

High-throughput

0.691

High

1363696

PDCL3
Phosducin-like protein 3

1

20

High-throughput

0.691

High

1363710

DTL
Denticleless protein homolog

1

20

High-throughput

0.691

High

1363713

TBD
Tubulin delta chain

1

20

High-throughput

0.691

High

1363722

STRAP
Serine-threonine kinase receptor-associated protein

1

20

High-throughput

0.691

High

1363691

STRAB
STE20-related kinase adapter protein beta

3

20

High-throughput

0.675

High

1363675

DAA10
Dynein axonemal assembly factor 10

2

5

High-throughput

0.675

High

923392

MK10
Mitogen-activated protein kinase 10

3

18

High-throughput

0.667

High

984222

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

2

20

High-throughput

0.628

High

1109945

HDAC1
Histone deacetylase 1

2

20

High-throughput

0.628

High

1187619

TTLL9
Probable tubulin polyglutamylase TTLL9

2

12

High-throughput

0.628

High

1363704

RHOF
Rho-related GTP-binding protein RhoF

2

1

High-throughput

0.628

High

1363709

SMOX
Spermine oxidase

2

1

High-throughput

0.628

High

1363715

CD11A
Cyclin-dependent kinase 11A

2

17

High-throughput

0.628

High

1363723

RAP2C
Ras-related protein Rap-2c

2

8

High-throughput

0.628

High

1363726

HCFC2
Host cell factor 2

2

11

High-throughput

0.628

High

1350322

MK15
Mitogen-activated protein kinase 15

2

11

High-throughput

0.621

High

1047926

TLE2
Transducin-like enhancer protein 2

1

20

High-throughput

0.618

High

1208941

DCA10
DDB1- and CUL4-associated factor 10

1

20

High-throughput

0.618

High

1351250

ACTT1
Actin-related protein T1

1

20

High-throughput

0.618

High

1352026

ACTT2
Actin-related protein T2

1

20

High-throughput

0.618

High

1363070

DDB2
DNA damage-binding protein 2

1

20

High-throughput

0.618

High

1363686

TBB6
Tubulin beta-6 chain

1

20

High-throughput

0.618

High

1363698

TBB1
Tubulin beta-1 chain

1

20

High-throughput

0.618

High

228617

STRN
Striatin

1

20

High-throughput

0.618

High

958318

ARP2
Actin-related protein 2

1

20

High-throughput

0.618

High

995730

ACTC
Actin, alpha cardiac muscle 1

1

17

High-throughput

0.618

High

1104234

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

20

High-throughput

0.618

High

1227168

A16L1
Autophagy-related protein 16-1

1

20

High-throughput

0.618

High

155791

TXND9
Thioredoxin domain-containing protein 9

2

19

High-throughput

0.611

High

1363701

EGLN3
Prolyl hydroxylase EGLN3

2

5

High-throughput

0.611

High

1315273

SEP12
Septin-12

3

8

High-throughput

0.609

High

1331403

PLPL1
Omega-hydroxyceramide transacylase

3

7

High-throughput

0.609

High

1363672

LOXL4
Lysyl oxidase homolog 4

3

14

High-throughput

0.609

High

1363667

RM38
Large ribosomal subunit protein mL38

2

0

High-throughput

0.602

High

64606

KLH33
Kelch-like protein 33

2

15

High-throughput

0.574

High

1134798

ODFP1
Outer dense fiber protein 1

2

5

High-throughput

0.574

High

1157629

RPE65
Retinoid isomerohydrolase

2

1

High-throughput

0.574

High

1203536

LRC10
Leucine-rich repeat-containing protein 10

2

5

High-throughput

0.574

High

1291938

WDR5B
WD repeat-containing protein 5B

2

20

High-throughput

0.574

High

1314858

KLD8A
Kelch domain-containing protein 8A

2

13

High-throughput

0.574

High

1363671

THOC3
THO complex subunit 3

2

20

High-throughput

0.574

High

1363720

KLDC2
Kelch domain-containing protein 2

2

18

High-throughput

0.574

High

190715

MPPD1
Metallophosphoesterase domain-containing protein 1

2

5

High-throughput

0.558

High

322670

KDM4B
Lysine-specific demethylase 4B

2

13

High-throughput

0.558

High

1332548

DC4L2
DDB1- and CUL4-associated factor 4-like protein 2

2

13

High-throughput

0.558

High

1363682

FYCO1
FYVE and coiled-coil domain-containing protein 1

2

14

High-throughput

0.558

High

1363719

2ABG
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform

1

20

High-throughput

0.554

High

1363688

TBB2B
Tubulin beta-2B chain

1

20

High-throughput

0.553

High

1363718

WDR37
WD repeat-containing protein 37

1

20

High-throughput

0.553

High

67564

MYH7B
Myosin-7B

1

5

High-throughput

0.536

High

732369

PRDX2
Peroxiredoxin-2

1

7

High-throughput

0.536

High

897060

MAP2
Methionine aminopeptidase 2

1

6

High-throughput

0.536

High

952006

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

1

20

High-throughput

0.536

High

983543

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

20

High-throughput

0.536

High

1143036

CDK10
Cyclin-dependent kinase 10

1

16

High-throughput

0.536

High

1218056

CBPC6
Cytosolic carboxypeptidase 6

1

5

High-throughput

0.536

High

1231176

TRI68
E3 ubiquitin-protein ligase TRIM68

1

6

High-throughput

0.536

High

1324343

PELI3
E3 ubiquitin-protein ligase pellino homolog 3

1

2

High-throughput

0.536

High

1325502

FBXW8
F-box/WD repeat-containing protein 8

1

20

Small-scale

0.536

High

1363685

DCTN5
Dynactin subunit 5

1

1

High-throughput

0.536

High

1363694

RAB6C
Ras-related protein Rab-6C

1

3

High-throughput

0.536

High

1363705

CAN10
Calpain-10

1

4

High-throughput

0.536

High

1363711

HDAC6
Protein deacetylase HDAC6

1

20

High-throughput

0.536

High

1363712

MIOX
Inositol oxygenase

1

2

High-throughput

0.536

High

1363725

MMAC
Cyanocobalamin reductase / alkylcobalamin dealkylase

1

4

High-throughput

0.536

High

1247273

WDR74
WD repeat-containing protein 74

1

20

High-throughput

0.514

High

1334156

POC1A
POC1 centriolar protein homolog A

1

20

High-throughput

0.514

High

1186931

KR194
Keratin-associated protein 19-4

1

0

High-throughput

0.513

High

1186964

KR151
Keratin-associated protein 15-1

1

0

High-throughput

0.513

High

1257089

PAXI1
PAX-interacting protein 1

1

6

High-throughput

0.504

High

1110950

ITPK1
Inositol-tetrakisphosphate 1-kinase

1

0

High-throughput

0.493

High

1351815

ACMSD
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase

1

0

High-throughput

0.493

High

51540

PL8L1
PLAC8-like protein 1

1

4

High-throughput

0.489

High

65948

LIRA5
Leukocyte immunoglobulin-like receptor subfamily A member 5

1

1

High-throughput

0.489

High

229277

ANGL7
Angiopoietin-related protein 7

1

4

High-throughput

0.489

High

261534

B4GT2
Beta-1,4-galactosyltransferase 2

1

1

High-throughput

0.489

High

290363

RFPL1
Ret finger protein-like 1

1

8

High-throughput

0.489

High

366233

HPTR
Haptoglobin-related protein

1

3

High-throughput

0.489

High

1095076

DAZ2
Deleted in azoospermia protein 2

1

6

High-throughput

0.489

High

1150302

TAF1C
TATA box-binding protein-associated factor RNA polymerase I subunit C

1

5

High-throughput

0.489

High

1187344

DC4L1
DDB1- and CUL4-associated factor 4-like protein 1

1

13

High-throughput

0.489

High

1200000

KLH26
Kelch-like protein 26

1

9

High-throughput

0.489

High

1212598

HECD3
E3 ubiquitin-protein ligase HECTD3

1

20

High-throughput

0.489

High

1212679

GT253
Inactive glycosyltransferase 25 family member 3

1

5

High-throughput

0.489

High

1322378

PGAM4
Probable phosphoglycerate mutase 4

1

7

High-throughput

0.489

High

1329264

MET27
Methyltransferase-like protein 27

1

1

High-throughput

0.489

High

1333559

SUMF2
Inactive C-alpha-formylglycine-generating enzyme 2

1

1

High-throughput

0.489

High

1335414

PAG15
Lysosomal phospholipase A and acyltransferase

1

3

High-throughput

0.489

High

1337451

FA83F
Protein FAM83F

1

3

High-throughput

0.489

High

1337769

LFNG
Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe

1

7

High-throughput

0.489

High

1363670

TRM61
tRNA

1

2

High-throughput

0.489

High

1363703

FOH1B
Putative N-acetylated-alpha-linked acidic dipeptidase

1

4

High-throughput

0.489

High

1363706

E41LA
Band 4.1-like protein 4A

1

5

High-throughput

0.489

High

1363714

HECD1
E3 ubiquitin-protein ligase HECTD1

1

11

High-throughput

0.489

High

132191

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

12

High-throughput

0.479

High

163648

GNB5
Guanine nucleotide-binding protein subunit beta-5

1

20

High-throughput

0.479

High

242449

PRKN
E3 ubiquitin-protein ligase parkin

1

11

High-throughput

0.479

High

315824

RECQ4
ATP-dependent DNA helicase Q4

1

9

High-throughput

0.479

High

339344

MET18
Histidine protein methyltransferase 1 homolog

1

4

High-throughput

0.479

High

351285

TTLL1
Polyglutamylase complex subunit TTLL1

1

12

High-throughput

0.479

High

583097

VATB1
V-type proton ATPase subunit B, kidney isoform

1

11

High-throughput

0.479

High

884375

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

1

High-throughput

0.479

High

888217

MCM2
DNA replication licensing factor MCM2

1

6

High-throughput

0.479

High

1053711

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

7

High-throughput

0.479

High

1057216

PRDX1
Peroxiredoxin-1

1

7

High-throughput

0.479

High

1113867

CUL3
Cullin-3

1

7

High-throughput

0.479

High

1194248

LARP7
La-related protein 7

1

5

High-throughput

0.479

High

1226716

2ABD
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

1

20

High-throughput

0.479

High

1242351

PLBL1
Phospholipase B-like 1

1

2

High-throughput

0.479

High

1363666

EFMT3
EEF1A lysine methyltransferase 3

1

20

High-throughput

0.479

High

1363668

MTMR8
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR8

1

5

High-throughput

0.479

High

1363674

CI072
Guanine nucleotide exchange factor C9orf72

1

5

High-throughput

0.479

High

1363676

CDK15
Cyclin-dependent kinase 15

1

19

High-throughput

0.479

High

1363695

GAN
Gigaxonin

1

11

High-throughput

0.479

High

1363716

MTMR6
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR6

1

5

High-throughput

0.479

High

1363717

SYFA
Phenylalanine--tRNA ligase alpha subunit

1

2

High-throughput

0.479

High

1363724

TTLL3
Tubulin monoglycylase TTLL3

1

12

High-throughput

0.479

High

1225993

ICE2
Little elongation complex subunit 2

1

0

High-throughput

0.458

High

1335994

SMIP6
Sperm microtubule inner protein 6

1

0

High-throughput

0.458

High

104017

F5GX28
Lysine-specific demethylase 4B

1

13

High-throughput

0.445

High

530141

TAU
Microtubule-associated protein tau

1

13

High-throughput

0.445

High

765751

BMI1
Polycomb complex protein BMI-1

1

20

High-throughput

0.445

High

1363677

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

4

High-throughput

0.445

High

325015

HEXI1
Protein HEXIM1

1

5

High-throughput

0.437

High

372708

MYC
Myc proto-oncogene protein

1

7

High-throughput

0.437

High

504816

F86B2
Putative protein N-methyltransferase FAM86B2

1

20

High-throughput

0.437

High

998614

H31
Histone H3.1

1

7

High-throughput

0.437

High

1155602

EZH2
Histone-lysine N-methyltransferase EZH2

1

20

High-throughput

0.437

High

1239457

H3C
Histone H3.3C

1

7

High-throughput

0.437

High

1353515

UBS3B
Ubiquitin-associated and SH3 domain-containing protein B

1

8

High-throughput

0.437

High

1355895

DUS19
Dual specificity protein phosphatase 19

1

4

High-throughput

0.437

High

1363663

TOPB1
DNA topoisomerase 2-binding protein 1

1

7

High-throughput

0.437

High

1363683

CF300
Cilia- and flagella-associated protein 300

1

1

High-throughput

0.437

High

1363699

PKHA4
Pleckstrin homology domain-containing family A member 4

1

13

High-throughput

0.437

High

1363700

DUS21
Dual specificity protein phosphatase 21

1

4

High-throughput

0.437

High

1331818

CIROZ
Ciliated left-right organizer ZP-N domains-containing protein

1

2

High-throughput

0.407

High

1363721

PHOCN
MOB-like protein phocein

1

7

High-throughput

0.407

High

1240629

PLB1
Phospholipase B1, membrane-associated

2

0

High-throughput

0.328

High

1363664

DNSL2
Deoxyribonuclease-1-like 2

2

0

High-throughput

0.318

High

49598

GXLT2
Glucoside xylosyltransferase 2

1

0

High-throughput

0.279

Low

634556

LMNB1
Lamin-B1

1

0

High-throughput

0.279

Low

922548

AP3M2
AP-3 complex subunit mu-2

1

0

High-throughput

0.279

Low

1363690

SCOT2
Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial

1

0

High-throughput

0.279

Low

1363697

ADAM7
Disintegrin and metalloproteinase domain-containing protein 7

1

0

High-throughput

0.279

Low

1363702

VRTN
Vertnin

1

0

High-throughput

0.279

Low

271198

ASTN2
Astrotactin-2

1

0

High-throughput

0.249

Low

946642

S26A5
Prestin

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025