HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: NLE1 (Q9NVX2)
Notchless protein homolog 1
Gene: NLE1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	26472760, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 485
+	Hs
		821387 TCPE_HUMAN (1-541): 0: 635: 100.00		TBL1Y_HUMAN (241-484): 3.26e-58: 202: 23.51
+	Hs
		821152 TCPE_HUMAN (1-541): 0: 635: 100.00		WDR5_HUMAN (2-231): 8.42e-54: 185: 19.92
+	Hs
		792942 TCPG_HUMAN (14-540): 0: 572: 33.15		LIS1_HUMAN (2-275): 4.65e-74: 241: 21.36
+	Hs
		826807 TCPG_HUMAN (14-540): 0: 572: 33.15		FBXW7_HUMAN (6-352): 2.75e-69: 236: 21.41
+	Hs
		826848 TCPG_HUMAN (14-540): 0: 572: 33.15		TBL1Y_HUMAN (241-484): 3.26e-58: 202: 23.51
+	Hs
		1306645 TCPH_HUMAN (12-539): 0: 570: 29.64		TBL1Y_HUMAN (241-484): 3.26e-58: 202: 23.51
+	Hs
		826601 TCPG_HUMAN (14-540): 0: 572: 33.15		WDR5_HUMAN (2-231): 8.42e-54: 185: 19.92
+	Hs
		903467 TCPH_HUMAN (12-539): 0: 570: 29.64		WDR5_HUMAN (2-231): 8.42e-54: 185: 19.92
+	Hs
		826748 TCPG_HUMAN (14-540): 0: 572: 33.15		WDR5B_HUMAN (300-484): 9.99e-52: 179: 32.97
+	Hs
		1202777 TCPH_HUMAN (12-539): 0: 570: 29.64		WDR5B_HUMAN (300-484): 9.99e-52: 179: 32.97
+	Hs
		821291 TCPE_HUMAN (1-541): 0: 635: 100.00		WDR86_HUMAN (361-483): 2.08e-22: 100: 24.39
+	Hs
		821326 TCPE_HUMAN (1-541): 0: 635: 100.00		POC1B_HUMAN (4-124): 2.13e-21: 98.5: 13.18
+	Hs
		821316 TCPE_HUMAN (1-541): 0: 635: 100.00		POC1A_HUMAN (4-85): 3.63e-17: 85.1: 13.42
+	Hs
		826743 TCPG_HUMAN (14-540): 0: 572: 33.15		WDR86_HUMAN (361-483): 2.08e-22: 100: 24.39
+	Hs
		826784 TCPG_HUMAN (14-540): 0: 572: 33.15		POC1B_HUMAN (4-124): 2.13e-21: 98.5: 13.18
+	Hs
		1198554 TCPH_HUMAN (12-539): 0: 570: 29.64		WDR86_HUMAN (361-483): 2.08e-22: 100: 24.39
+	Hs
		826772 TCPG_HUMAN (14-540): 0: 572: 33.15		POC1A_HUMAN (4-85): 3.63e-17: 85.1: 13.42
+	Hs
		1240450 TCPH_HUMAN (12-539): 0: 570: 29.64		POC1A_HUMAN (4-85): 3.63e-17: 85.1: 13.42
+	Cr
		65492 A8J7J2_CHLRE (6-540): 0: 588: 66.17		MUT11_CHLRE (106-252): 6.71e-11: 65.9: 30.20
+	Cr
		65475 A8II42_CHLRE (15-534): 0: 577: 34.10		MUT11_CHLRE (106-252): 6.71e-11: 65.9: 30.20