HitPredict

Interactor 1: NEST (P48681)
Nestin
Gene: NES

Interactor 2: ECT2 (Q9H8V3)
Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene)
Gene: ECT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1621 Hs			1 914
+	Hs
		443814 VIME_HUMAN (8-343): 3.05e-118: 382: 28.32		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		728517 MYH11_HUMAN (470-1525): 1.94e-33: 143: 10.43		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		725023 MYH9_HUMAN (729-1459): 1.22e-24: 115: 10.48		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		535572 GFAP_HUMAN (8-316): 8.2e-22: 102: 30.35		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		1061251 NUMA1_HUMAN (818-1473): 5.43e-19: 96.5: 10.02		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		409257 K2C8_HUMAN (7-315): 1.79e-122: 395: 23.68		ARHGC_HUMAN (316-874): 1.5e-78: 281: 16.35
+	Hs
		409270 K2C8_HUMAN (7-315): 1.79e-122: 395: 23.68		PKHG1_HUMAN (367-887): 3.48e-78: 280: 16.79
+	Hs
		821783 NEST_HUMAN (1-1621): 1.09e-115: 404: 100.00		ARHGJ_HUMAN (378-821): 6.57e-75: 264: 18.90
+	Hs
		443876 VIME_HUMAN (8-343): 3.05e-118: 382: 28.32		PKHG1_HUMAN (367-887): 3.48e-78: 280: 16.79
+	Hs
		1273273 CP250_HUMAN (48-1491): 3.97e-42: 172: 11.11		ARHG2_HUMAN (249-775): 2e-83: 291: 15.02
+	Hs
		724913 MYH9_HUMAN (729-1459): 1.22e-24: 115: 10.48		ARG28_HUMAN (216-807): 7.17e-88: 309: 12.32
+	Hs
		1356647 MYH13_HUMAN (549-1526): 1.29e-30: 134: 10.01		PKHG1_HUMAN (367-887): 3.48e-78: 280: 16.79
+	Hs
		50564 MYH9_HUMAN (729-1459): 1.22e-24: 115: 10.48		PKHG3_HUMAN (394-892): 2.49e-76: 273: 18.53
+	Hs
		535403 GFAP_HUMAN (8-316): 8.2e-22: 102: 30.35		ITSN1_HUMAN (402-782): 1.02e-76: 276: 18.14
+	Hs
		422187 NFL_HUMAN (7-323): 1.31e-18: 93.6: 27.95		ITSN1_HUMAN (402-782): 1.02e-76: 276: 18.14
+	Hs
		724971 MYH9_HUMAN (729-1459): 1.22e-24: 115: 10.48		ARHGH_HUMAN (398-726): 8.05e-68: 249: 23.82
+	Hs
		422237 NFL_HUMAN (7-323): 1.31e-18: 93.6: 27.95		NGEF_HUMAN (354-827): 7.02e-77: 267: 17.15
+	Hs
		422224 NFL_HUMAN (7-323): 1.31e-18: 93.6: 27.95		ARHGJ_HUMAN (378-821): 6.57e-75: 264: 18.90
+	Hs
		1021851 CP250_HUMAN (48-1491): 3.97e-42: 172: 11.11		ABR_HUMAN (463-641): 7.42e-16: 84.3: 30.27
+	Hs
		422165 NFL_HUMAN (7-323): 1.31e-18: 93.6: 27.95		ECT2L_HUMAN (453-721): 2.8e-23: 108: 28.93