HitPredict

Interactor 1: HSP13 (P48723)
Heat shock 70 kDa protein 13 (Heat shock protein family A member 13) (Microsomal stress-70 protein ATPase core) (Stress-70 protein chaperone microsome-associated 60 kDa protein)
Gene: HSPA13

Interactor 2: HYOU1 (Q9Y4L1)
Hypoxia up-regulated protein 1 (150 kDa oxygen-regulated protein) (ORP-150) (170 kDa glucose-regulated protein) (GRP-170) (Heat shock protein family H member 4)
Gene: HYOU1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HSP70~HSP70
Common GO terms	GO:0005524 - ATP binding GO:0005783 - endoplasmic reticulum GO:0070062 - extracellular exosome GO:0140662 - ATP-dependent protein folding chaperone
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 471 Hs			1 999
+	Hs
		505010 HSP7C_HUMAN (28-469): 0: 584: 36.91		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		821880 HSP13_HUMAN (1-471): 0: 602: 100.00		HS105_HUMAN (33-960): 0: 812: 24.46
+	Hs
		504490 HSP7C_HUMAN (28-469): 0: 584: 36.91		HS105_HUMAN (33-960): 0: 812: 24.46
+	Hs
		1120566 Q53FA3_HUMAN (26-470): 0: 581: 37.56		HS105_HUMAN (33-960): 0: 812: 24.46
+	Hs
		714034 HS71L_HUMAN (26-470): 0: 580: 37.56		HS105_HUMAN (33-960): 0: 812: 24.46
+	Hs
		320802 HSP7C_HUMAN (28-469): 0: 584: 36.91		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		564020 HSP76_HUMAN (26-470): 0: 585: 36.89		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Hs
		503544 HSP7C_HUMAN (28-469): 0: 584: 36.91		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Hs
		713910 HS71L_HUMAN (26-470): 0: 580: 37.56		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Hs
		483777 HS71B_HUMAN (28-470): 0: 578: 37.50		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Dm
		332632 HSP7A_DROME (28-469): 0: 578: 36.02		HSP68_DROME (33-607): 3.18e-61: 222: 29.89
+	Hs
		503389 HSP76_HUMAN (26-470): 0: 585: 36.89		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		503543 HSP7C_HUMAN (28-469): 0: 584: 36.91		HS71L_HUMAN (682-814): 9.92e-31: 131: 15.04
+	Hs
		503315 HSP7C_HUMAN (28-469): 0: 584: 36.91		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Mm
		926115 HSP7C_MOUSE (28-469): 0: 584: 36.91		HSP7C_MOUSE (682-815): 1.96e-30: 130: 16.42
+	Hs
		564046 HSP76_HUMAN (26-470): 0: 585: 36.89		HSP72_HUMAN (682-814): 8.57e-30: 128: 16.54
+	Hs
		503752 HSP7C_HUMAN (28-469): 0: 584: 36.91		HSP72_HUMAN (682-814): 8.57e-30: 128: 16.54
+	Hs
		871593 Q53FC7_HUMAN (26-470): 0: 582: 36.44		HSP72_HUMAN (682-814): 8.57e-30: 128: 16.54