HitPredict

Interactor 1: IDHP (P48735)
Isocitrate dehydrogenase [NADP], mitochondrial (IDH) (EC 1.1.1.42) (ICD-M) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)
Gene: IDH2

Interactor 2: IDHP (P48735)
Isocitrate dehydrogenase [NADP], mitochondrial (IDH) (EC 1.1.1.42) (ICD-M) (IDP) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase)
Gene: IDH2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 37071682, 23558173
Identification Methods cross-linking study, x-ray crystallography
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Iso_dh~Iso_dh
Common GO terms GO:0000287 - magnesium ion binding
GO:0004450 - isocitrate dehydrogenase (NADP+) activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0005777 - peroxisome
and 9 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 452
Hs

1 452
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024