HitPredict

Interactor 1: PK3CG (P48736)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PI3-kinase subunit gamma) (PI3K-gamma) (PI3Kgamma) (PtdIns-3-kinase subunit gamma) (EC 2.7.1.137) (EC 2.7.1.153) (EC 2.7.1.154) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma) (PtdIns-3-kinase subunit p110-gamma) (p110gamma) (Phosphoinositide-3-kinase catalytic gamma polypeptide) (Serine/threonine protein kinase PIK3CG) (EC 2.7.11.1) (p120-PI3K)
Gene: PIK3CG

Interactor 2: GAB1 (Q13480)
GRB2-associated-binding protein 1 (GRB2-associated binder 1) (Growth factor receptor bound protein 2-associated protein 1)
Gene: GAB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.27	0.60	0.408

Property	Details
Experiments	11453982
Identification Methods	unspecified method
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001525 - angiogenesis GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1102 Hs			1 694
+	Hs
		787224 PK3CA_HUMAN (23-1093): 0: 1030: 32.92		GAB1_HUMAN (1-694): 0: 547: 100.00
+	Mm
		193576 PK3CD_MOUSE (38-1091): 0: 1016: 30.94		GAB2_MOUSE (3-691): 8.7e-141: 429: 38.33
+	Hs
		787406 PK3CB_HUMAN (38-1091): 0: 928: 30.96		GAB2_HUMAN (3-691): 2.24e-153: 461: 39.01
+	Mm
		1207246 PK3CB_MOUSE (38-1091): 0: 949: 31.33		GAB2_MOUSE (3-691): 8.7e-141: 429: 38.33
+	Hs
		787309 PK3CA_HUMAN (23-1093): 0: 1030: 32.92		PKHA5_HUMAN (5-476): 6.15e-67: 240: 13.00
+	Hs
		128872 P3C2A_HUMAN (166-1095): 0: 762: 27.12		PKHA7_HUMAN (5-485): 5.86e-74: 260: 12.07
+	Hs
		128920 P3C2A_HUMAN (166-1095): 0: 762: 27.12		MYO10_HUMAN (2-301): 2.1e-29: 127: 14.89