HitPredict

Interactor 1: VHL (P40337)
von Hippel-Lindau disease tumor suppressor (Protein G7) (pVHL)
Gene: VHL

Interactor 2: UB2V1 (Q13404)
Ubiquitin-conjugating enzyme E2 variant 1 (UEV-1) (CROC-1) (TRAF6-regulated IKK activator 1 beta Uev1A)
Gene: UBE2V1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17353931
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006355 - regulation of DNA-templated transcription GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 213 Hs			1 147
+	Hs
		822543 VHL_HUMAN (1-213): 3.46e-146: 407: 100.00		UB2D1_HUMAN (12-147): 6.79e-59: 181: 24.27
+	Hs
		822585 VHL_HUMAN (1-213): 3.46e-146: 407: 100.00		UB2D2_HUMAN (12-146): 7.46e-58: 178: 22.96
+	Hs
		822560 VHL_HUMAN (1-213): 3.46e-146: 407: 100.00		UB2D3_HUMAN (12-146): 2.66e-57: 176: 22.96
+	Hs
		822595 VHL_HUMAN (1-213): 3.46e-146: 407: 100.00		UBC9_HUMAN (9-145): 4.64e-55: 171: 21.01