HitPredict

Interactor 1: LHX1 (P48742)
LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1) (hLim-1)
Gene: LHX1

Interactor 2: SSBP3 (Q9BWW4)
Single-stranded DNA-binding protein 3 (Sequence-specific single-stranded-DNA-binding protein)
Gene: SSBP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	26186194, 28514442, 33961781, 35140242
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005667 - transcription regulator complex GO:0048382 - mesendoderm development GO:2000744 - positive regulation of anterior head development
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 406 Hs			1 388
+	Hs
		822672 LHX1_HUMAN (1-406): 1.12e-95: 293: 100.00		SSBP4_HUMAN (5-388): 9.47e-57: 192: 69.25
+	Hs
		822624 LHX1_HUMAN (1-406): 1.12e-95: 293: 100.00		SSBP2_HUMAN (3-388): 2.7e-44: 158: 77.26
+	Hs
		822688 LHX1_HUMAN (1-406): 1.12e-95: 293: 100.00		CHD7_HUMAN (99-332): 1.72e-32: 131: 17.60
+	Hs
		1314910 LHX3_HUMAN (1-374): 4.86e-60: 201: 33.95		SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00
+	Hs
		1281179 LHX4_HUMAN (1-398): 3.46e-58: 196: 31.49		SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00
+	Hs
		1314903 LHX9_HUMAN (2-307): 2.45e-54: 186: 29.05		SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00
+	Hs
		238119 LMX1B_HUMAN (2-347): 3.79e-54: 186: 27.59		SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00
+	Hs
		1314659 LHX3_HUMAN (1-374): 4.86e-60: 201: 33.95		SSBP4_HUMAN (5-388): 9.47e-57: 192: 69.25
+	Hs
		1281178 LHX4_HUMAN (1-398): 3.46e-58: 196: 31.49		SSBP4_HUMAN (5-388): 9.47e-57: 192: 69.25
+	Hs
		1314654 LHX9_HUMAN (2-307): 2.45e-54: 186: 29.05		SSBP4_HUMAN (5-388): 9.47e-57: 192: 69.25
+	Hs
		238118 LMX1B_HUMAN (2-347): 3.79e-54: 186: 27.59		SSBP4_HUMAN (5-388): 9.47e-57: 192: 69.25
+	Hs
		946671 LHX3_HUMAN (1-374): 4.86e-60: 201: 33.95		SSBP2_HUMAN (3-388): 2.7e-44: 158: 77.26
+	Mm
		291998 LMX1B_MOUSE (2-347): 2.22e-54: 186: 29.48		Q3U4B1_MOUSE (1-388): 1.81e-48: 169: 62.66
+	Hs
		946655 LHX4_HUMAN (1-398): 3.46e-58: 196: 31.49		SSBP2_HUMAN (3-388): 2.7e-44: 158: 77.26
+	Mm
		1321889 LMX1A_MOUSE (2-347): 9.49e-56: 189: 28.41		SSBP2_MOUSE (3-388): 9.79e-45: 159: 77.00
+	Mm
		292010 LMX1B_MOUSE (2-347): 2.22e-54: 186: 29.48		SSBP2_MOUSE (3-388): 9.79e-45: 159: 77.00
+	Hs
		238106 LMX1B_HUMAN (2-347): 3.79e-54: 186: 27.59		SSBP2_HUMAN (3-388): 2.7e-44: 158: 77.26
+	Hs
		1350240 LHX3_HUMAN (1-374): 4.86e-60: 201: 33.95		CHD7_HUMAN (99-332): 1.72e-32: 131: 17.60
+	Hs
		1281194 LHX4_HUMAN (1-398): 3.46e-58: 196: 31.49		CHD7_HUMAN (99-332): 1.72e-32: 131: 17.60
+	Dm
		112549 M9NCY1_DROME (1-376): 1.87e-55: 189: 31.10		Q9VEB9_DROME (1-297): 1.64e-34: 134: 51.55