HitPredict

Interactor 1: RFX1 (P48743)
RFX-like DNA-binding protein RFX1
Gene: RFX1

Interactor 2: ISW2 (Q08773)
ISWI chromatin-remodeling complex ATPase ISW2 (EC 3.6.4.-) (Imitation switch protein 2)
Gene: ISW2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.588

Property	Details
Experiments	11805826, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 811 Sc			1 1120
+	Sc
		744885 RFX1_YEAST (1-811): 0: 890: 100.00		ISW1_YEAST (1-1109): 0: 835: 48.59
+	Sc
		603325 RFX1_YEAST (1-811): 0: 890: 100.00		SNF2_YEAST (43-870): 0: 656: 30.57
+	Sc
		696229 RFX1_YEAST (1-811): 0: 890: 100.00		STH1_YEAST (55-642): 1.69e-125: 419: 42.11
+	Hs
		1147487 ARID2_HUMAN (281-533): 2.34e-48: 188: 18.53		CHD7_HUMAN (9-1110): 0: 814: 25.52
+	Dm
		51526 A1Z6M0_DROME (158-525): 3.96e-67: 245: 14.17		BRM_DROME (107-765): 0: 645: 37.17
+	Hs
		846995 ARID2_HUMAN (281-533): 2.34e-48: 188: 18.53		SMCA4_HUMAN (115-892): 0: 681: 30.39
+	Hs
		846798 ARID2_HUMAN (281-533): 2.34e-48: 188: 18.53		SMCA2_HUMAN (172-649): 4.23e-124: 418: 44.73