HitPredict

Interactor 1: AGRE5 (P48960)
Adhesion G protein-coupled receptor E5 (Leukocyte antigen CD97) (CD antigen CD97) [Cleaved into: Adhesion G protein-coupled receptor E5 subunit alpha; Adhesion G protein-coupled receptor E5 subunit beta]
Gene: ADGRE5

Interactor 2: AGRE2 (Q9UHX3)
Adhesion G protein-coupled receptor E2 (EGF-like module receptor 2) (EGF-like module-containing mucin-like hormone receptor-like 2) (CD antigen CD312)
Gene: ADGRE2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_2~7tm_2, EGF_CA~EGF_CA
Common GO terms GO:0004930 - G protein-coupled receptor activity
GO:0005509 - calcium ion binding
GO:0005886 - plasma membrane
GO:0007155 - cell adhesion
GO:0006954 - inflammatory response
and 4 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 835
Hs

1 823
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Last updated: 15 Jul 2024