Protein: ATG3
Ubiquitin-like-conjugating enzyme ATG3 (EC 2.3.2.-) (Autophagy-related protein 3) (APG3-like) (hApg3) (Protein PC3-96)

Gene: ATG3
Organism: Homo sapiens
Interactions: 80
UniProt ID: Q9NT62

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0000407 - phagophore assembly site
GO:0000422 - autophagy of mitochondrion
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

334252

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

7

7

Small-scale

0.964

High

317685

ATG12
Ubiquitin-like protein ATG12

14

6

Small-scale

0.761

High

1431324

ATG5
Autophagy protein 5

7

4

Small-scale

0.749

High

1428384

MLP3B
Microtubule-associated protein 1 light chain 3 beta

7

19

Small-scale

0.748

High

1433213

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

7

19

Small-scale

0.746

High

952359

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

5

19

Small-scale

0.730

High

1227539

A16L1
Autophagy-related protein 16-1

5

2

High-throughput

0.722

High

328171

GBRAP
Gamma-aminobutyric acid receptor-associated protein

4

19

Small-scale

0.711

High

1430730

ATG10
Ubiquitin-like-conjugating enzyme ATG10

1

3

High-throughput

0.691

High

64581

MP3B2
Microtubule-associated protein 1 light chain 3 beta 2

3

19

High-throughput

0.662

High

1430341

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

2

19

Small-scale

0.639

High

1226600

MAP1S
Microtubule-associated protein 1S

2

2

High-throughput

0.628

High

893532

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

2

0

High-throughput

0.602

High

1201073

ACTBL
Beta-actin-like protein 2

2

0

High-throughput

0.602

High

1258320

MOB2
MOB kinase activator 2

2

0

High-throughput

0.580

High

1449502

ATG3
Ubiquitin-like-conjugating enzyme ATG3

1

3

High-throughput

0.575

High

347954

BAG3
BAG family molecular chaperone regulator 3

2

0

Small-scale

0.559

High

374964

RASH
GTPase HRas

1

1

High-throughput

0.536

High

861308

MAP1B
Microtubule-associated protein 1B

1

2

High-throughput

0.536

High

1163238

H2B2E
Histone H2B type 2-E

1

2

High-throughput

0.536

High

1407906

ANM1
Protein arginine N-methyltransferase 1

1

2

High-throughput

0.536

High

1417417

MLP3C
Microtubule-associated protein 1 light chain 3 gamma

1

19

High-throughput

0.536

High

1449503

ATG4B
Cysteine protease ATG4B

1

1

High-throughput

0.536

High

193048

CFLAR
CASP8 and FADD-like apoptosis regulator

1

1

Small-scale

0.515

High

984301

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

1

High-throughput

0.515

High

215662

EMC8
ER membrane protein complex subunit 8

1

0

High-throughput

0.513

High

611988

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.513

High

1122049

EFR3A
Protein EFR3 homolog A

1

0

High-throughput

0.513

High

1216052

TTBK1
Tau-tubulin kinase 1

1

0

High-throughput

0.513

High

1326109

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.513

High

1420888

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

0

High-throughput

0.513

High

1117507

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

0

High-throughput

0.493

High

1211654

FBP1L
Formin-binding protein 1-like

1

0

Small-scale

0.493

High

1126768

BECN1
Beclin-1

1

0

Small-scale

0.480

High

173435

XPO1
Exportin-1

1

1

High-throughput

0.479

High

243062

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

946892

H2B1D
Histone H2B type 1-D

1

2

High-throughput

0.479

High

1007546

KRT85
Keratin, type II cuticular Hb5

1

1

High-throughput

0.479

High

1067756

EP300
Histone acetyltransferase p300

1

1

High-throughput

0.479

High

1255732

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

1368495

CBP
CREB-binding protein

1

1

Small-scale

0.479

High

133804

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

0

High-throughput

0.458

High

260512

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

272488

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.458

High

378580

IL1B
Interleukin-1 beta

1

0

Small-scale

0.458

High

533778

CLUS
Clusterin

1

0

Small-scale

0.458

High

831501

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

976595

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.458

High

986756

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.458

High

1054794

SUH
Recombining binding protein suppressor of hairless

1

0

High-throughput

0.458

High

1121345

TRI14
Tripartite motif-containing protein 14

1

0

High-throughput

0.458

High

1280542

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

142426

PEX7
Peroxisomal targeting signal 2 receptor

1

1

High-throughput

0.445

High

1208899

H2B2F
Histone H2B type 2-F

1

2

High-throughput

0.445

High

125630

LEG9
Galectin-9

1

0

High-throughput

0.426

High

1209706

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1416725

OSB11
Oxysterol-binding protein-related protein 11

1

0

High-throughput

0.426

High

1397177

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

1

High-throughput

0.407

High

387904

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

0

High-throughput

0.279

Low

484662

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

925986

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

0

High-throughput

0.279

Low

1052915

HME1
Homeobox protein engrailed-1

1

0

High-throughput

0.279

Low

1200337

ANR39
Ankyrin repeat domain-containing protein 39

1

0

High-throughput

0.279

Low

1208243

SPXN4
Sperm protein associated with the nucleus on the X chromosome N4

1

0

High-throughput

0.279

Low

1232736

H2A2A
Histone H2A type 2-A

1

0

High-throughput

0.279

Low

1279492

GP141
Probable G-protein coupled receptor 141

1

0

High-throughput

0.279

Low

1280175

TCPR1
Tectonin beta-propeller repeat-containing protein 1

1

0

High-throughput

0.279

Low

1328466

CMIP6
Ciliary microtubule inner protein 6

1

0

High-throughput

0.279

Low

1336365

CCNY
Cyclin-Y

1

0

High-throughput

0.279

Low

1341237

IKBD
NF-kappa-B inhibitor delta

1

0

High-throughput

0.279

Low

1394349

ZN414
Zinc finger protein 414

1

0

High-throughput

0.279

Low

569140

T2FB
General transcription factor IIF subunit 2

1

0

High-throughput

0.249

Low

1211901

FKB15
FK506-binding protein 15

1

0

High-throughput

0.249

Low

1365516

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

0

High-throughput

0.249

Low

330336

VENTX
Homeobox protein VENTX

1

0

High-throughput

0.232

Low

1104128

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.232

Low

1219475

SLX4I
Protein SLX4IP

1

0

High-throughput

0.232

Low

1410238

SLX1
Structure-specific endonuclease subunit SLX1

1

0

High-throughput

0.232

Low

1435016

TM231
Transmembrane protein 231

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025