HitPredict

Interactor 1: ROA1 (P49312)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (HDP-1) (Helix-destabilizing protein) (Single-strand-binding protein) (Topoisomerase-inhibitor suppressed) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: Hnrnpa1

Interactor 2: SRSF9 (Q9D0B0)
Serine/arginine-rich splicing factor 9 (Splicing factor, arginine/serine-rich 9)
Gene: SRSF9

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	34133714
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000380 - alternative mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 320 Mm			1 222
+	Hs
		453328 ROA1_HUMAN (1-188): 1.85e-57: 191: 100.00		SRSF6_HUMAN (16-177): 7.21e-51: 169: 36.67
+	Hs
		453309 ROA1_HUMAN (1-188): 1.85e-57: 191: 100.00		SRSF4_HUMAN (16-170): 1.9e-47: 164: 39.52
+	Hs
		516358 ROA2_HUMAN (1-286): 4.23e-58: 192: 58.31		PABP1_HUMAN (13-194): 3.27e-44: 158: 20.00
+	Hs
		453107 ROA1_HUMAN (1-188): 1.85e-57: 191: 100.00		PABP1_HUMAN (13-194): 3.27e-44: 158: 20.00
+	Hs
		453331 ROA1_HUMAN (1-188): 1.85e-57: 191: 100.00		PABP4_HUMAN (13-192): 2.39e-44: 158: 19.68
+	Hs
		516339 PABP1_HUMAN (6-193): 1.56e-41: 154: 17.46		PABP1_HUMAN (13-194): 3.27e-44: 158: 20.00
+	Hs
		516495 PABP1_HUMAN (6-193): 1.56e-41: 154: 17.46		PABP4_HUMAN (13-192): 2.39e-44: 158: 19.68
+	Hs
		516511 HNRPD_HUMAN (4-184): 1.67e-39: 144: 42.54		PABP1_HUMAN (13-194): 3.27e-44: 158: 20.00
+	Sc
		376899 PABP_YEAST (2-186): 3.83e-41: 152: 22.22		NOP3_YEAST (8-180): 7.59e-38: 137: 27.68
+	Hs
		201707 MSI1H_HUMAN (2-320): 2.52e-59: 196: 26.98		RBM4B_HUMAN (6-103): 3.57e-18: 83.3: 20.41
+	Hs
		453327 ROA1_HUMAN (1-188): 1.85e-57: 191: 100.00		SRSF9_HUMAN (99-217): 8.42e-17: 77.6: 17.89
+	Hs
		453308 ROA1_HUMAN (1-188): 1.85e-57: 191: 100.00		SRSF1_HUMAN (98-180): 3.9e-14: 71: 21.84
+	Hs
		516674 PABP1_HUMAN (6-193): 1.56e-41: 154: 17.46		RBM4_HUMAN (5-147): 1.61e-19: 87.2: 17.33
+	Hs
		516493 PABP1_HUMAN (6-193): 1.56e-41: 154: 17.46		SRSF9_HUMAN (99-217): 8.42e-17: 77.6: 17.89
+	Hs
		516689 PABP1_HUMAN (6-193): 1.56e-41: 154: 17.46		PABP3_HUMAN (102-190): 1.25e-14: 74.1: 15.63
+	Hs
		516471 PABP1_HUMAN (6-193): 1.56e-41: 154: 17.46		TIAR_HUMAN (104-193): 3.08e-14: 72.6: 11.58
+	Mm
		665745 PABP1_MOUSE (6-193): 1.9e-41: 154: 17.46		TIA1_MOUSE (106-194): 6e-14: 71.8: 11.70
+	Hs
		516478 PABP1_HUMAN (6-193): 1.56e-41: 154: 17.46		SRSF1_HUMAN (98-180): 3.9e-14: 71: 21.84
+	Sc
		376562 PABP_YEAST (2-186): 3.83e-41: 152: 22.22		PABP_YEAST (113-193): 3.33e-14: 72.6: 20.46
+	Hs
		963520 HNRPD_HUMAN (4-184): 1.67e-39: 144: 42.54		TIAR_HUMAN (104-193): 3.08e-14: 72.6: 11.58