HitPredict

Interactor 1: NASP (P49321)
Nuclear autoantigenic sperm protein (NASP)
Gene: NASP

Interactor 2: H33 (P84243)
Histone H3.3
Gene: H3-3A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.751

Property	Details
Experiments	28514442, 33961781, 25416956, 36089195, 36949045, 36652389, 14718166, 20504901
Identification Methods	affinity chromatography technology, two hybrid, proximity labelling technology, cross-linking study, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly GO:0008584 - male gonad development GO:0032991 - protein-containing complex
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 788 Hs			1 136
+	Hs
		825812 NASP_HUMAN (1-788): 1.94e-140: 435: 100.00		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		825835 NASP_HUMAN (1-788): 1.94e-140: 435: 100.00		H31T_HUMAN (1-136): 2.58e-59: 181: 93.38
+	Hs
		825843 NASP_HUMAN (1-788): 1.94e-140: 435: 100.00		H32_HUMAN (1-136): 5.32e-59: 180: 97.06
+	Hs
		825837 NASP_HUMAN (1-788): 1.94e-140: 435: 100.00		H37_HUMAN (1-136): 4.54e-57: 175: 94.12
+	Hs
		825838 NASP_HUMAN (1-788): 1.94e-140: 435: 100.00		H3C_HUMAN (1-136): 1.99e-56: 173: 95.59
+	Mm
		69829 B1AU75_MOUSE (1-788): 4.14e-117: 373: 79.62		H31_MOUSE (1-136): 3.08e-60: 183: 96.32
+	Mm
		69831 B1AU75_MOUSE (1-788): 4.14e-117: 373: 79.62		H33_MOUSE (1-136): 1.12e-59: 182: 100.00
+	Mm
		69830 B1AU75_MOUSE (1-788): 4.14e-117: 373: 79.62		H32_MOUSE (1-136): 5.32e-59: 180: 97.06
+	Hs
		934881 NIPBL_HUMAN (80-756): 2.33e-100: 343: 12.41		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		952407 NIPBL_HUMAN (80-756): 2.33e-100: 343: 12.41		H33_HUMAN (1-136): 1.12e-59: 182: 100.00
+	Hs
		828271 NIPBL_HUMAN (80-756): 2.33e-100: 343: 12.41		CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76
+	Hs
		935049 TITIN_HUMAN (205-754): 1.24e-13: 77.7: 9.70		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Hs
		1174610 TITIN_HUMAN (205-754): 1.24e-13: 77.7: 9.70		H32_HUMAN (1-136): 5.32e-59: 180: 97.06
+	Hs
		934906 WDR87_HUMAN (115-735): 6.05e-10: 65.4: 16.16		H31_HUMAN (1-136): 3.08e-60: 183: 96.32
+	Sp
		457188 SIM3_SCHPO (426-669): 1.95e-10: 65.4: 21.46		H31_SCHPO (1-136): 1.12e-57: 177: 91.91
+	Sp
		1358017 SIM3_SCHPO (426-669): 1.95e-10: 65.4: 21.46		CENPA_SCHPO (26-133): 9.54e-42: 136: 63.16