HitPredict

Interactor 1: TCPG (P49368)
T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Chaperonin containing T-complex polypeptide 1 subunit 3) (hTRiC5)
Gene: CCT3

Interactor 2: JAK3 (P52333)
Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)
Gene: JAK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	25852190
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0005856 - cytoskeleton
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 545 Hs			1 1124
+	Hs
		433290 TCPG_HUMAN (1-545): 0: 640: 100.00		YES_HUMAN (784-1109): 7.17e-99: 326: 29.36
+	Hs
		411642 TCPG_HUMAN (1-545): 0: 640: 100.00		LCK_HUMAN (794-1110): 1.37e-97: 321: 30.50
+	Hs
		412086 TCPG_HUMAN (1-545): 0: 640: 100.00		FYN_HUMAN (790-1109): 4.99e-97: 320: 29.60
+	Hs
		454809 TCPG_HUMAN (1-545): 0: 640: 100.00		FGR_HUMAN (783-1110): 2.27e-93: 310: 28.88
+	Hs
		826575 TCPG_HUMAN (1-545): 0: 640: 100.00		BLK_HUMAN (784-1105): 3.14e-89: 298: 29.63
+	Hs
		411833 TCPH_HUMAN (2-536): 0: 574: 31.18		LCK_HUMAN (794-1110): 1.37e-97: 321: 30.50
+	Hs
		412325 TCPH_HUMAN (2-536): 0: 574: 31.18		FYN_HUMAN (790-1109): 4.99e-97: 320: 29.60
+	Hs
		454845 TCPH_HUMAN (2-536): 0: 574: 31.18		FGR_HUMAN (783-1110): 2.27e-93: 310: 28.88
+	Hs
		411639 TCPE_HUMAN (4-530): 0: 559: 32.52		LCK_HUMAN (794-1110): 1.37e-97: 321: 30.50
+	Hs
		412084 TCPE_HUMAN (4-530): 0: 559: 32.52		FYN_HUMAN (790-1109): 4.99e-97: 320: 29.60
+	Hs
		846519 TCPH_HUMAN (2-536): 0: 574: 31.18		BLK_HUMAN (784-1105): 3.14e-89: 298: 29.63
+	Hs
		454808 TCPE_HUMAN (4-530): 0: 559: 32.52		FGR_HUMAN (783-1110): 2.27e-93: 310: 28.88
+	Hs
		821128 TCPE_HUMAN (4-530): 0: 559: 32.52		BLK_HUMAN (784-1105): 3.14e-89: 298: 29.63
+	Hs
		669143 TCPG_HUMAN (1-545): 0: 640: 100.00		TYK2_HUMAN (828-1122): 5.53e-34: 144: 20.62
+	Hs
		826628 TCPG_HUMAN (1-545): 0: 640: 100.00		ACK1_HUMAN (525-790): 4.96e-16: 85.5: 29.14
+	Hs
		669197 TCPH_HUMAN (2-536): 0: 574: 31.18		TYK2_HUMAN (828-1122): 5.53e-34: 144: 20.62
+	Hs
		383691 TCPG_HUMAN (1-545): 0: 640: 100.00		ERBB2_HUMAN (527-780): 1.84e-13: 77.4: 25.00
+	Hs
		669142 TCPE_HUMAN (4-530): 0: 559: 32.52		TYK2_HUMAN (828-1122): 5.53e-34: 144: 20.62
+	Gg
		94466 TCPH_CHICK (2-534): 0: 579: 31.48		KSYK_CHICK (527-773): 4.4e-18: 91.7: 26.95
+	Hs
		821180 TCPE_HUMAN (4-530): 0: 559: 32.52		ACK1_HUMAN (525-790): 4.96e-16: 85.5: 29.14