Protein: FKH1
Fork head protein homolog 1

Gene: FKH1
Organism: Saccharomyces cerevisiae S288C
Interactions: 60
UniProt ID: P40466

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

824980

FKH1
Fork head protein homolog 1

2

17

Small-scale

0.815

High

734263

DBF4
DDK kinase regulatory subunit DBF4

1

1

Small-scale

0.740

High

824981

MPH1
ATP-dependent DNA helicase MPH1

4

9

Small-scale

0.701

High

364575

CDK1
Cyclin-dependent kinase 1

1

4

High-throughput

0.691

High

585955

CSK21
Casein kinase II subunit alpha

1

4

High-throughput

0.691

High

622965

CSK22
Casein kinase II subunit alpha'

1

4

High-throughput

0.691

High

649972

SIN3
Transcriptional regulatory protein SIN3

3

5

Small-scale

0.669

High

824983

FKH2
Fork head protein homolog 2

1

18

Small-scale

0.647

High

735511

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

3

High-throughput

0.618

High

820989

FDO1
Protein FDO1

2

0

Small-scale

0.588

High

745650

ORC2
Origin recognition complex subunit 2

2

5

Small-scale

0.584

High

824989

ORC1
Origin recognition complex subunit 1

2

4

Small-scale

0.584

High

381129

H2B1
Histone H2B.1

1

2

High-throughput

0.536

High

382144

H4
Histone H4

1

4

High-throughput

0.536

High

555316

EI2BD
Translation initiation factor eIF2B subunit delta

1

3

High-throughput

0.536

High

575347

EI2BA
Translation initiation factor eIF2B subunit alpha

1

3

High-throughput

0.536

High

600691

SEC2
Rab guanine nucleotide exchange factor SEC2

1

1

High-throughput

0.536

High

722002

XPO1
Exportin-1

1

9

High-throughput

0.536

High

738656

EI2BB
Translation initiation factor eIF2B subunit beta

1

3

High-throughput

0.536

High

812860

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

1

3

High-throughput

0.536

High

813333

MBP1
Transcription factor MBP1

1

7

High-throughput

0.536

High

478622

IF2B
Eukaryotic translation initiation factor 2 subunit beta

1

0

High-throughput

0.513

High

632903

IF2A
Eukaryotic translation initiation factor 2 subunit alpha

1

0

High-throughput

0.513

High

763081

RRP1
Ribosomal RNA-processing protein 1

1

0

High-throughput

0.513

High

824985

FYV8
Protein FYV8

1

0

High-throughput

0.513

High

824988

YG1B
Uncharacterized protein YGR017W

1

0

High-throughput

0.513

High

824993

MCE1
mRNA-capping enzyme subunit alpha

1

0

High-throughput

0.513

High

598411

TUP1
General transcriptional corepressor TUP1

1

10

Small-scale

0.501

High

518047

SSBP1
Single-stranded nucleic acid-binding protein

1

5

High-throughput

0.500

High

645440

XRN1
5'-3' exoribonuclease 1

1

1

High-throughput

0.500

High

585291

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

1

High-throughput

0.489

High

807767

CSK2C
Casein kinase II subunit beta'

1

3

High-throughput

0.489

High

824984

CSK2B
Casein kinase II subunit beta

1

3

High-throughput

0.489

High

615019

GLN3
Nitrogen regulatory protein GLN3

1

11

Small-scale

0.481

High

824999

NDD1
Nuclear division defective protein 1

1

1

Small-scale

0.481

High

824992

ACT
Actin

1

0

High-throughput

0.479

High

825000

RUVB2
RuvB-like protein 2

1

0

High-throughput

0.479

High

667095

CG22
G2/mitotic-specific cyclin-2

1

4

Small-scale

0.479

High

707286

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

824982

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.479

High

824990

ORC3
Origin recognition complex subunit 3

1

1

Small-scale

0.479

High

824991

ORC4
Origin recognition complex subunit 4

1

4

Small-scale

0.479

High

824996

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

816991

SPC25
Kinetochore protein SPC25

1

0

High-throughput

0.460

High

805513

ORC6
Origin recognition complex subunit 6

1

0

Small-scale

0.458

High

824987

ORC5
Origin recognition complex subunit 5

1

0

Small-scale

0.458

High

824998

APC5
Anaphase-promoting complex subunit 5

1

0

Small-scale

0.458

High

554933

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

2

High-throughput

0.457

High

524159

HSP71
Heat shock protein SSA1

1

9

High-throughput

0.445

High

545126

SSB1
Ribosome-associated molecular chaperone SSB1

1

9

High-throughput

0.445

High

670796

SIS1
Protein SIS1

1

4

High-throughput

0.445

High

818929

SSB2
Ribosome-associated molecular chaperone SSB2

1

9

High-throughput

0.445

High

824995

RNH2B
Ribonuclease H2 subunit B

1

0

High-throughput

0.438

High

654787

URE2
Transcriptional regulator URE2

2

0

Small-scale

0.320

High

744750

MG101
Mitochondrial genome maintenance protein MGM101

2

0

Small-scale

0.318

High

824986

NET1
Nucleolar protein NET1

1

0

High-throughput

0.279

Low

824997

ECM30
Protein ECM30

1

0

Small-scale

0.251

Low

677431

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low

824994

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025