HitPredict

Interactor 1: TCPG (P49368)
T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Chaperonin containing T-complex polypeptide 1 subunit 3) (hTRiC5)
Gene: CCT3

Interactor 2: CDK18 (Q07002)
Cyclin-dependent kinase 18 (EC 2.7.11.22) (Cell division protein kinase 18) (PCTAIRE-motif protein kinase 3) (Serine/threonine-protein kinase PCTAIRE-3)
Gene: CDK18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 545 Hs			1 474
+	Hs
		625228 TCPG_HUMAN (1-545): 0: 640: 100.00		CDK2_HUMAN (141-436): 1.07e-146: 422: 52.69
+	Hs
		989714 TCPH_HUMAN (2-536): 0: 574: 31.18		CDK18_HUMAN (1-474): 1.57e-165: 477: 100.00
+	Hs
		821179 TCPE_HUMAN (4-530): 0: 559: 32.52		CDK18_HUMAN (1-474): 1.57e-165: 477: 100.00
+	Hs
		826623 TCPG_HUMAN (1-545): 0: 640: 100.00		CDK5_HUMAN (141-431): 4.4e-133: 387: 55.29
+	Hs
		573231 TCPA_HUMAN (10-533): 0: 549: 33.09		CDK18_HUMAN (1-474): 1.57e-165: 477: 100.00
+	Hs
		625579 TCPH_HUMAN (2-536): 0: 574: 31.18		CDK2_HUMAN (141-436): 1.07e-146: 422: 52.69
+	Hs
		625220 TCPE_HUMAN (4-530): 0: 559: 32.52		CDK2_HUMAN (141-436): 1.07e-146: 422: 52.69
+	Hs
		415042 TCPH_HUMAN (2-536): 0: 574: 31.18		CDK1_HUMAN (141-430): 6.84e-137: 397: 51.54
+	Hs
		573132 TCPA_HUMAN (10-533): 0: 549: 33.09		CDK2_HUMAN (141-436): 1.07e-146: 422: 52.69
+	Hs
		960322 TCPH_HUMAN (2-536): 0: 574: 31.18		CDK5_HUMAN (141-431): 4.4e-133: 387: 55.29
+	Hs
		414817 TCPE_HUMAN (4-530): 0: 559: 32.52		CDK1_HUMAN (141-430): 6.84e-137: 397: 51.54
+	Hs
		414725 TCPA_HUMAN (10-533): 0: 549: 33.09		CDK1_HUMAN (141-430): 6.84e-137: 397: 51.54
+	Hs
		821173 TCPE_HUMAN (4-530): 0: 559: 32.52		CDK5_HUMAN (141-431): 4.4e-133: 387: 55.29
+	Hs
		573225 TCPA_HUMAN (10-533): 0: 549: 33.09		CDK5_HUMAN (141-431): 4.4e-133: 387: 55.29
+	Sc
		339699 TCPH_YEAST (5-543): 0: 544: 30.29		CDK1_YEAST (139-427): 1.47e-128: 376: 50.00
+	Hs
		843169 TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56		CDK18_HUMAN (1-474): 1.57e-165: 477: 100.00
+	Hs
		625246 TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56		CDK2_HUMAN (141-436): 1.07e-146: 422: 52.69
+	Hs
		414827 TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56		CDK1_HUMAN (141-430): 6.84e-137: 397: 51.54
+	Hs
		843341 TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56		CDK15_HUMAN (107-452): 1.54e-131: 389: 51.29
+	Hs
		843162 TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56		CDK5_HUMAN (141-431): 4.4e-133: 387: 55.29