HitPredict

Interactor 1: TCPG (P49368)
T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Chaperonin containing T-complex polypeptide 1 subunit 3) (hTRiC5)
Gene: CCT3

Interactor 2: MP2K5 (Q13163)
Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)
Gene: MAP2K5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 545 Hs			1 448
+	Hs
		1026826 TCPH_HUMAN (2-536): 0: 574: 31.18		MP2K5_HUMAN (1-448): 4.77e-153: 443: 100.00
+	Hs
		681738 TCPG_HUMAN (1-545): 0: 640: 100.00		AKT1_HUMAN (59-444): 3.89e-123: 368: 17.82
+	Hs
		821189 TCPE_HUMAN (4-530): 0: 559: 32.52		MP2K5_HUMAN (1-448): 4.77e-153: 443: 100.00
+	Hs
		573240 TCPA_HUMAN (10-533): 0: 549: 33.09		MP2K5_HUMAN (1-448): 4.77e-153: 443: 100.00
+	Hs
		826636 TCPG_HUMAN (1-545): 0: 640: 100.00		STK4_HUMAN (146-445): 8.05e-108: 329: 31.09
+	Hs
		826963 TCPG_HUMAN (1-545): 0: 640: 100.00		STK24_HUMAN (163-421): 2.25e-106: 324: 35.61
+	Hs
		681999 TCPH_HUMAN (2-536): 0: 574: 31.18		AKT1_HUMAN (59-444): 3.89e-123: 368: 17.82
+	Hs
		681735 TCPE_HUMAN (4-530): 0: 559: 32.52		AKT1_HUMAN (59-444): 3.89e-123: 368: 17.82
+	Hs
		573141 TCPA_HUMAN (10-533): 0: 549: 33.09		AKT1_HUMAN (59-444): 3.89e-123: 368: 17.82
+	Hs
		1023098 TCPH_HUMAN (2-536): 0: 574: 31.18		STK4_HUMAN (146-445): 8.05e-108: 329: 31.09
+	Hs
		1306764 TCPH_HUMAN (2-536): 0: 574: 31.18		STK24_HUMAN (163-421): 2.25e-106: 324: 35.61
+	Hs
		1306717 TCPH_HUMAN (2-536): 0: 574: 31.18		STK26_HUMAN (155-421): 7.86e-106: 321: 35.66
+	Hs
		821480 TCPE_HUMAN (4-530): 0: 559: 32.52		STK24_HUMAN (163-421): 2.25e-106: 324: 35.61
+	Hs
		573237 TCPA_HUMAN (10-533): 0: 549: 33.09		STK4_HUMAN (146-445): 8.05e-108: 329: 31.09
+	Hs
		573550 TCPA_HUMAN (10-533): 0: 549: 33.09		STK24_HUMAN (163-421): 2.25e-106: 324: 35.61
+	Hs
		131548 TCPA_HUMAN (10-533): 0: 549: 33.09		STK25_HUMAN (163-424): 1.64e-105: 321: 35.58
+	Hs
		843180 TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56		MP2K5_HUMAN (1-448): 4.77e-153: 443: 100.00
+	Hs
		681747 TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56		AKT1_HUMAN (59-444): 3.89e-123: 368: 17.82
+	Hs
		843450 TCPD_HUMAN (16-524): 1.08e-90: 290: 34.56		STK24_HUMAN (163-421): 2.25e-106: 324: 35.61