HitPredict

Interactor 1: ARRB1 (P49407)
Beta-arrestin-1 (Arrestin beta-1) (Non-visual arrestin-2)
Gene: ARRB1

Interactor 2: STK38 (Q15208)
Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1)
Gene: STK38

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	17620599
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 418 Hs			1 465
+	Hs
		827295 ARRB1_HUMAN (1-418): 0: 716: 100.00		ST38L_HUMAN (11-465): 5.84e-178: 508: 87.47
+	Hs
		685962 ARRB2_HUMAN (1-407): 0: 626: 76.15		STK38_HUMAN (1-465): 0: 527: 100.00
+	Hs
		681739 ARRB1_HUMAN (1-418): 0: 716: 100.00		AKT1_HUMAN (36-447): 7.66e-138: 406: 27.06
+	Mm
		682118 ARRB1_MOUSE (1-418): 0: 703: 98.57		AKT1_MOUSE (50-447): 2.25e-137: 405: 27.16
+	Hs
		681683 ARRB2_HUMAN (1-407): 0: 626: 76.15		AKT1_HUMAN (36-447): 7.66e-138: 406: 27.06
+	Hs
		682136 ARRB2_HUMAN (1-407): 0: 626: 76.15		AKT2_HUMAN (6-447): 2.1e-137: 405: 24.45
+	Mm
		682122 ARRB2_MOUSE (1-407): 0: 615: 75.00		AKT1_MOUSE (50-447): 2.25e-137: 405: 27.16
+	Hs
		827193 ARRB1_HUMAN (1-418): 0: 716: 100.00		ROCK1_HUMAN (70-415): 3.59e-79: 270: 42.90