HitPredict

Interactor 1: CENPA (P49450)
Histone H3-like centromeric protein A (Centromere autoantigen A) (Centromere protein A) (CENP-A)
Gene: CENPA

Interactor 2: HDGR2 (Q7Z4V5)
Hepatoma-derived growth factor-related protein 2 (HDGF-related protein 2) (HRP-2) (Hepatoma-derived growth factor 2) (HDGF-2)
Gene: HDGFL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~PWWP
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 140 Hs			1 671
+	Hs
		828350 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		NSD1_HUMAN (2-668): 2.86e-90: 310: 12.29
+	Hs
		935129 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		NSD1_HUMAN (2-668): 2.86e-90: 310: 12.29
+	Hs
		934923 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		HDGR2_HUMAN (1-671): 9.52e-82: 274: 100.00
+	Hs
		331748 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		NSD2_HUMAN (3-440): 5.42e-66: 238: 11.70
+	Hs
		331780 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		NSD2_HUMAN (3-440): 5.42e-66: 238: 11.70
+	Hs
		331823 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		NSD2_HUMAN (3-440): 5.42e-66: 238: 11.70
+	Hs
		828367 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		NSD3_HUMAN (4-413): 2.6e-62: 227: 11.66
+	Hs
		935205 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		NSD3_HUMAN (4-413): 2.6e-62: 227: 11.66
+	Hs
		1157224 H3C_HUMAN (5-134): 5.15e-52: 162: 47.69		NSD3_HUMAN (4-413): 2.6e-62: 227: 11.66
+	Hs
		265969 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		PSIP1_HUMAN (1-553): 1.35e-54: 197: 23.49
+	Hs
		265990 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		PSIP1_HUMAN (1-553): 1.35e-54: 197: 23.49
+	Hs
		828177 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		MSH6_HUMAN (4-299): 4.35e-45: 175: 12.98
+	Hs
		855452 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		MSH6_HUMAN (4-299): 4.35e-45: 175: 12.98
+	Hs
		935364 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		ZMYD8_HUMAN (6-605): 7.73e-40: 159: 14.24
+	Hs
		828247 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		GLYR1_HUMAN (6-212): 3.25e-36: 145: 21.10
+	Hs
		934827 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		GLYR1_HUMAN (6-212): 3.25e-36: 145: 21.10
+	Hs
		850895 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		HDGF_HUMAN (3-234): 8.81e-26: 108: 35.78
+	Hs
		828271 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		NIPBL_HUMAN (100-662): 1.42e-17: 89.7: 16.10
+	Hs
		935417 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		HDGR3_HUMAN (2-194): 5.06e-22: 96.6: 43.43
+	Hs
		934881 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		NIPBL_HUMAN (100-662): 1.42e-17: 89.7: 16.10