HitPredict

Interactor 1: UBE2A (P49459)
Ubiquitin-conjugating enzyme E2 A (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme A) (RAD6 homolog A) (HR6A) (hHR6A) (Ubiquitin carrier protein A) (Ubiquitin-protein ligase A)
Gene: UBE2A

Interactor 2: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	28031328, 22592529
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 152 Hs			1 126
+	Mm
		1145473 UBE2A_MOUSE (1-152): 3.88e-76: 225: 100.00		H2B2B_MOUSE (1-126): 2.34e-54: 168: 97.62
+	Hs
		828971 UBE2A_HUMAN (1-152): 3.88e-76: 225: 100.00		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		707552 UBE2A_HUMAN (1-152): 3.88e-76: 225: 100.00		H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41
+	Hs
		828968 UBE2A_HUMAN (1-152): 3.88e-76: 225: 100.00		H2B1D_HUMAN (1-126): 3.5e-53: 164: 98.41
+	Mm
		927791 UBE2B_MOUSE (1-151): 3.28e-74: 219: 96.03		H2B2B_MOUSE (1-126): 2.34e-54: 168: 97.62
+	Hs
		927767 UBE2B_HUMAN (1-151): 3.28e-74: 219: 96.03		H2B1A_HUMAN (1-126): 3.43e-46: 147: 85.04
+	Sc
		355730 UBC2_YEAST (1-150): 2.29e-73: 218: 69.33		H2B2_YEAST (3-125): 4.73e-37: 124: 71.55
+	Sc
		355294 UBC2_YEAST (1-150): 2.29e-73: 218: 69.33		H2B1_YEAST (3-125): 1.81e-36: 122: 71.55