HitPredict

Interactor 1: PPM1F (P49593)
Protein phosphatase 1F (EC 3.1.3.16) (Ca(2+)/calmodulin-dependent protein kinase phosphatase) (CaM-kinase phosphatase) (CaMKPase) (Partner of PIX 2) (Protein fem-2 homolog) (hFem-2)
Gene: PPM1F

Interactor 2: ROR1 (Q01973)
Inactive tyrosine-protein kinase transmembrane receptor ROR1 (Neurotrophic tyrosine kinase, receptor-related 1)
Gene: ROR1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.50	0.494

Property	Details
Experiments	28065597
Identification Methods	two hybrid, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 454 Hs			1 937
+	Hs
		829443 PPM1F_HUMAN (1-454): 6.13e-177: 504: 100.00		ROR2_HUMAN (1-936): 0: 665: 55.33
+	Hs
		273422 PPM1B_HUMAN (141-449): 1.86e-100: 310: 23.88		ROR1_HUMAN (30-937): 0: 775: 100.00
+	Hs
		728600 PPM1A_HUMAN (141-445): 1.24e-103: 315: 25.38		ROR2_HUMAN (1-936): 0: 665: 55.33
+	Hs
		273423 PPM1B_HUMAN (141-449): 1.86e-100: 310: 23.88		ROR2_HUMAN (1-936): 0: 665: 55.33
+	Hs
		829448 PPM1F_HUMAN (1-454): 6.13e-177: 504: 100.00		ERBB4_HUMAN (113-932): 1.7e-142: 458: 18.75
+	Hs
		728586 PPM1A_HUMAN (141-445): 1.24e-103: 315: 25.38		VGFR2_HUMAN (38-911): 4.89e-150: 480: 16.41
+	Hs
		273355 PPM1B_HUMAN (141-449): 1.86e-100: 310: 23.88		FGFR1_HUMAN (19-798): 2.01e-155: 480: 17.93
+	Hs
		273384 PPM1B_HUMAN (141-449): 1.86e-100: 310: 23.88		VGFR2_HUMAN (38-911): 4.89e-150: 480: 16.41
+	Zm
		4976 A0A1D6DVE9_MAIZE (106-417): 7.02e-107: 321: 28.18		A0A1D6IZ90_MAIZE (202-792): 6.09e-148: 454: 15.10
+	Hs
		728610 PPM1A_HUMAN (141-445): 1.24e-103: 315: 25.38		ERBB4_HUMAN (113-932): 1.7e-142: 458: 18.75
+	Hs
		273436 PPM1B_HUMAN (141-449): 1.86e-100: 310: 23.88		ERBB4_HUMAN (113-932): 1.7e-142: 458: 18.75
+	Hs
		384485 PPM1F_HUMAN (1-454): 6.13e-177: 504: 100.00		NTRK1_HUMAN (478-748): 5.71e-72: 255: 46.89
+	Hs
		435583 PPM1F_HUMAN (1-454): 6.13e-177: 504: 100.00		IGF1R_HUMAN (467-742): 3.41e-54: 207: 39.71
+	Hs
		385250 PPM1E_HUMAN (48-438): 3.08e-121: 372: 50.26		NTRK1_HUMAN (478-748): 5.71e-72: 255: 46.89
+	Hs
		829445 PPM1F_HUMAN (1-454): 6.13e-177: 504: 100.00		PTK7_HUMAN (58-526): 1e-09: 64.8: 15.50
+	Hs
		435562 PPM1A_HUMAN (141-445): 1.24e-103: 315: 25.38		IGF1R_HUMAN (467-742): 3.41e-54: 207: 39.71
+	Hs
		728673 PPM1A_HUMAN (141-445): 1.24e-103: 315: 25.38		ALK_HUMAN (404-746): 1.74e-53: 205: 35.20
+	Hs
		601473 PPM1A_HUMAN (141-445): 1.24e-103: 315: 25.38		FGFR2_HUMAN (22-182): 1.27e-18: 93.3: 19.02
+	Hs
		728604 PPM1A_HUMAN (141-445): 1.24e-103: 315: 25.38		PTK7_HUMAN (58-526): 1e-09: 64.8: 15.50
+	Hs
		273427 PPM1B_HUMAN (141-449): 1.86e-100: 310: 23.88		PTK7_HUMAN (58-526): 1e-09: 64.8: 15.50