Interactor 1: MAD1 (P40957)
Spindle assembly checkpoint component MAD1 (Mitotic arrest deficient protein 1)
Gene: MAD1
Interactor 2: MAD2 (P40958)
Mitotic spindle checkpoint component MAD2 (Mitotic MAD2 protein)
Gene: MAD2
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.976 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10436016, 12473689, 10837255, 16554755, 16818718, 37968396, 39079532, 16429126 |
| Identification Methods | molecular sieving, coimmunoprecipitation, affinity chromatography technology, pull down, biochemical, two hybrid, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | HORMA~MAD |
| Common GO terms | GO:0000776 - kinetochore GO:0007094 - mitotic spindle assembly checkpoint signaling GO:0044774 - mitotic DNA integrity checkpoint signaling GO:0051301 - cell division |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
