HitPredict

Interactor 1: HXA1 (P49639)
Homeobox protein Hox-A1 (Homeobox protein Hox-1F)
Gene: HOXA1

Interactor 2: SPRE1 (Q7Z699)
Sprouty-related, EVH1 domain-containing protein 1 (Spred-1) (hSpred1)
Gene: SPRED1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.50	0.470

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 335 Hs			1 444
+	Hs
		446904 HXC4_HUMAN (142-328): 1.95e-36: 133: 32.09		SPRE1_HUMAN (1-444): 3.81e-177: 504: 100.00
+	Hs
		1151093 Q6FHY5_HUMAN (54-335): 8.47e-32: 122: 19.67		SPRE1_HUMAN (1-444): 3.81e-177: 504: 100.00
+	Hs
		838086 MEOX2_HUMAN (54-335): 1.36e-31: 122: 20.33		SPRE1_HUMAN (1-444): 3.81e-177: 504: 100.00
+	Hs
		453057 HXB7_HUMAN (86-298): 3.66e-32: 121: 24.20		SPRE1_HUMAN (1-444): 3.81e-177: 504: 100.00
+	Hs
		837817 MEOX1_HUMAN (42-312): 2.44e-30: 117: 22.88		SPRE1_HUMAN (1-444): 3.81e-177: 504: 100.00
+	Hs
		829924 HXA1_HUMAN (1-302): 1.66e-60: 198: 100.00		Q7Z783_HUMAN (169-433): 7.64e-65: 213: 16.61
+	Hs
		208106 HXA1_HUMAN (1-302): 1.66e-60: 198: 100.00		SPY2_HUMAN (169-433): 5.08e-63: 208: 16.61
+	Hs
		208329 HXA1_HUMAN (1-302): 1.66e-60: 198: 100.00		SPY1_HUMAN (199-433): 1.45e-56: 191: 19.69
+	Hs
		830014 HXA1_HUMAN (1-302): 1.66e-60: 198: 100.00		SPY4_HUMAN (168-435): 8.08e-54: 183: 14.97
+	Hs
		538731 HXB2_HUMAN (188-327): 1.31e-40: 147: 39.01		HOME1_HUMAN (11-343): 1.82e-65: 215: 12.89
+	Hs
		208413 HXA1_HUMAN (1-302): 1.66e-60: 198: 100.00		SPY3_HUMAN (201-435): 5.31e-43: 154: 16.79
+	Hs
		538744 HXB2_HUMAN (188-327): 1.31e-40: 147: 39.01		HOME2_HUMAN (11-230): 3.06e-59: 199: 12.11
+	Hs
		838087 MEOX2_HUMAN (54-335): 1.36e-31: 122: 20.33		Q7Z783_HUMAN (169-433): 7.64e-65: 213: 16.61
+	Hs
		208107 MEOX2_HUMAN (54-335): 1.36e-31: 122: 20.33		SPY2_HUMAN (169-433): 5.08e-63: 208: 16.61
+	Hs
		208331 MEOX2_HUMAN (54-335): 1.36e-31: 122: 20.33		SPY1_HUMAN (199-433): 1.45e-56: 191: 19.69
+	Hs
		208375 Q6FHY5_HUMAN (54-335): 8.47e-32: 122: 19.67		SPY1_HUMAN (199-433): 1.45e-56: 191: 19.69
+	Hs
		447297 HXB5_HUMAN (48-300): 1.8e-32: 123: 24.44		HOME3_HUMAN (11-333): 1.13e-50: 177: 11.68
+	Hs
		837852 MEOX1_HUMAN (42-312): 2.44e-30: 117: 22.88		HOME3_HUMAN (11-333): 1.13e-50: 177: 11.68
+	Hs
		208414 MEOX2_HUMAN (54-335): 1.36e-31: 122: 20.33		SPY3_HUMAN (201-435): 5.31e-43: 154: 16.79
+	Hs
		208426 Q6FHY5_HUMAN (54-335): 8.47e-32: 122: 19.67		SPY3_HUMAN (201-435): 5.31e-43: 154: 16.79