HitPredict

Interactor 1: CXCR3 (P49682)
C-X-C chemokine receptor type 3 (CXC-R3) (CXCR-3) (CKR-L2) (G protein-coupled receptor 9) (Interferon-inducible protein 10 receptor) (IP-10 receptor) (CD antigen CD183)
Gene: CXCR3

Interactor 2: CCL11 (P51671)
Eotaxin (C-C motif chemokine 11) (Eosinophil chemotactic protein) (Small-inducible cytokine A11)
Gene: CCL11

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	9660793
Identification Methods	biochemical
Interaction Type	physical association

Property	Details
Interacting Pfam domains	7tm_1~IL8
Common GO terms	GO:0007155 - cell adhesion GO:0006935 - chemotaxis GO:0006954 - inflammatory response GO:0007186 - G protein-coupled receptor signaling pathway GO:0045766 - positive regulation of angiogenesis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 368 Hs			1 97
+	Hs
		849654 CCR5_HUMAN (39-366): 2e-87: 269: 31.94		CCL13_HUMAN (1-96): 8.14e-35: 116: 64.29
+	Hs
		561733 CCR5_HUMAN (39-366): 2e-87: 269: 31.94		CL3L1_HUMAN (1-92): 5.52e-34: 113: 39.36
+	Hs
		486239 CCR5_HUMAN (39-366): 2e-87: 269: 31.94		CCL3_HUMAN (1-92): 6.38e-33: 111: 38.71
+	Hs
		849505 CCR5_HUMAN (39-366): 2e-87: 269: 31.94		CCL11_HUMAN (1-97): 5.99e-33: 111: 100.00
+	Hs
		849647 CCR5_HUMAN (39-366): 2e-87: 269: 31.94		CCL8_HUMAN (1-97): 7.48e-33: 111: 69.70
+	Hs
		526565 CCR5_HUMAN (39-366): 2e-87: 269: 31.94		CCL4_HUMAN (1-91): 2.6e-32: 109: 39.79
+	Hs
		849648 CCR5_HUMAN (39-366): 2e-87: 269: 31.94		CCL7_HUMAN (17-96): 5.98e-31: 106: 67.07
+	Hs
		528211 CCR5_HUMAN (39-366): 2e-87: 269: 31.94		CCL2_HUMAN (1-96): 1.64e-30: 105: 70.41
+	Hs
		486237 CCR3_HUMAN (43-336): 1.14e-80: 252: 33.45		CCL3_HUMAN (1-92): 6.38e-33: 111: 38.71
+	Hs
		526564 CCR3_HUMAN (43-336): 1.14e-80: 252: 33.45		CCL4_HUMAN (1-91): 2.6e-32: 109: 39.79
+	Hs
		528254 CCR5_HUMAN (39-366): 2e-87: 269: 31.94		CCL5_HUMAN (1-90): 8.3e-25: 90.8: 42.86
+	Hs
		528210 CCR3_HUMAN (43-336): 1.14e-80: 252: 33.45		CCL2_HUMAN (1-96): 1.64e-30: 105: 70.41
+	Hs
		849653 CCR5_HUMAN (39-366): 2e-87: 269: 31.94		CCL17_HUMAN (6-89): 2.53e-23: 86.9: 32.14
+	Hs
		118813 CCR3_HUMAN (43-336): 1.14e-80: 252: 33.45		CCL24_HUMAN (1-97): 6.19e-29: 101: 35.05
+	Hs
		180161 CCR5_HUMAN (39-366): 2e-87: 269: 31.94		CCL16_HUMAN (1-87): 1.97e-21: 83.1: 30.44
+	Hs
		134292 CCR7_HUMAN (21-364): 1.4e-85: 265: 36.39		CCL21_HUMAN (17-97): 2.54e-22: 85.8: 32.14
+	Hs
		686791 CCR7_HUMAN (21-364): 1.4e-85: 265: 36.39		CCL19_HUMAN (18-96): 1.57e-20: 80: 23.75
+	Mm
		486212 CCR8_MOUSE (40-335): 9.74e-83: 257: 32.32		CCL1_MOUSE (1-88): 6e-23: 86.1: 30.34
+	Hs
		528252 CCR3_HUMAN (43-336): 1.14e-80: 252: 33.45		CCL5_HUMAN (1-90): 8.3e-25: 90.8: 42.86
+	Hs
		134725 CCR7_HUMAN (21-364): 1.4e-85: 265: 36.39		CCL22_HUMAN (21-90): 8.24e-19: 75.7: 31.51