HitPredict

Interactor 1: PSB3 (P49720)
Proteasome subunit beta type-3 (Proteasome chain 13) (Proteasome component C10-II) (Proteasome theta chain)
Gene: PSMB3

Interactor 2: PLK1 (P53350)
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)
Gene: PLK1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	11205743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 205 Hs			1 603
+	Hs
		656573 PSB6_HUMAN (7-200): 4.63e-70: 215: 22.68		PLK1_HUMAN (1-603): 0: 617: 100.00
+	Hs
		656685 PSB5_HUMAN (8-197): 1.9e-66: 206: 22.63		PLK1_HUMAN (1-603): 0: 617: 100.00
+	Hs
		594484 PSB1_HUMAN (2-205): 1.85e-65: 203: 23.94		PLK1_HUMAN (1-603): 0: 617: 100.00
+	Hs
		637653 PSA2_HUMAN (8-205): 1.92e-64: 200: 14.85		PLK1_HUMAN (1-603): 0: 617: 100.00
+	Hs
		656180 PSA5_HUMAN (8-203): 6.92e-64: 199: 12.20		PLK1_HUMAN (1-603): 0: 617: 100.00
+	Ce
		711591 PSB3_CAEEL (1-205): 2.37e-65: 201: 50.73		PLK1_CAEEL (22-599): 0: 536: 50.58
+	Ce
		711768 PBS5_CAEEL (7-197): 3.8e-63: 198: 24.75		PLK1_CAEEL (22-599): 0: 536: 50.58
+	Ce
		711253 PSB1_CAEEL (2-205): 7.23e-63: 197: 24.07		PLK1_CAEEL (22-599): 0: 536: 50.58
+	Ce
		711692 Q966I8_CAEEL (7-194): 3.23e-54: 174: 23.40		PLK1_CAEEL (22-599): 0: 536: 50.58
+	Zm
		13498 A0A1D6NV82_MAIZE (5-194): 8.74e-66: 205: 26.13		A0A1D6FU50_MAIZE (40-415): 5.72e-138: 420: 29.77
+	Zm
		43396 A0A1D6PJW1_MAIZE (8-190): 1.22e-65: 205: 13.68		A0A1D6QH07_MAIZE (47-400): 2.85e-139: 414: 28.05
+	Zm
		8048 B4FRQ7_MAIZE (3-205): 5.72e-67: 206: 21.30		A0A1D6EK73_MAIZE (37-348): 4.21e-137: 410: 33.55
+	Hs
		160446 PSB3_HUMAN (1-205): 1.02e-71: 218: 100.00		AURKA_HUMAN (28-307): 4.39e-43: 160: 32.17
+	Hs
		160395 PSB5_HUMAN (8-197): 1.9e-66: 206: 22.63		AURKA_HUMAN (28-307): 4.39e-43: 160: 32.17
+	Hs
		160376 PSB1_HUMAN (2-205): 1.85e-65: 203: 23.94		AURKA_HUMAN (28-307): 4.39e-43: 160: 32.17
+	Hs
		160390 PSA2_HUMAN (8-205): 1.92e-64: 200: 14.85		AURKA_HUMAN (28-307): 4.39e-43: 160: 32.17
+	Hs
		160394 PSA5_HUMAN (8-203): 6.92e-64: 199: 12.20		AURKA_HUMAN (28-307): 4.39e-43: 160: 32.17