HitPredict

Interactor 1: PSB3 (P49720)
Proteasome subunit beta type-3 (Proteasome chain 13) (Proteasome component C10-II) (Proteasome theta chain)
Gene: PSMB3

Interactor 2: FBX7 (Q9Y3I1)
F-box only protein 7
Gene: FBXO7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	27497298, 27503909, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 205 Hs			1 522
+	Hs
		656663 PSB6_HUMAN (7-200): 4.63e-70: 215: 22.68		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		656798 PSB5_HUMAN (8-197): 1.9e-66: 206: 22.63		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		594668 PSB1_HUMAN (2-205): 1.85e-65: 203: 23.94		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		637761 PSA2_HUMAN (8-205): 1.92e-64: 200: 14.85		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		656346 PSA5_HUMAN (8-203): 6.92e-64: 199: 12.20		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		656144 PSB9_HUMAN (6-200): 1.41e-63: 197: 23.08		FBX7_HUMAN (1-522): 0: 1102: 100.00