HitPredict

Interactor 1: PSB3 (P49720)
Proteasome subunit beta type-3 (Proteasome chain 13) (Proteasome component C10-II) (Proteasome theta chain)
Gene: PSMB3

Interactor 2: UCHL5 (Q9Y5K5)
Ubiquitin carboxyl-terminal hydrolase isozyme L5 (UCH-L5) (EC 3.4.19.12) (Ubiquitin C-terminal hydrolase UCH37) (Ubiquitin thioesterase L5)
Gene: UCHL5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.714

Property	Details
Experiments	35271311, 34761751, 19615732, 18922472, 19490896
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 205 Hs			1 329
+	Hs
		656667 PSB6_HUMAN (7-200): 4.63e-70: 215: 22.68		UCHL5_HUMAN (1-329): 1.1e-175: 491: 100.00
+	Hs
		656802 PSB5_HUMAN (8-197): 1.9e-66: 206: 22.63		UCHL5_HUMAN (1-329): 1.1e-175: 491: 100.00
+	Hs
		594671 PSB1_HUMAN (2-205): 1.85e-65: 203: 23.94		UCHL5_HUMAN (1-329): 1.1e-175: 491: 100.00
+	Hs
		637763 PSA2_HUMAN (8-205): 1.92e-64: 200: 14.85		UCHL5_HUMAN (1-329): 1.1e-175: 491: 100.00
+	Hs
		656348 PSA5_HUMAN (8-203): 6.92e-64: 199: 12.20		UCHL5_HUMAN (1-329): 1.1e-175: 491: 100.00
+	Hs
		656147 PSB9_HUMAN (6-200): 1.41e-63: 197: 23.08		UCHL5_HUMAN (1-329): 1.1e-175: 491: 100.00
+	Sp
		1358105 PSA5_SCHPO (8-204): 2.58e-65: 203: 12.56		UBLH2_SCHPO (7-325): 1.13e-114: 335: 38.77
+	Sp
		195134 PSB1_SCHPO (8-199): 1.63e-65: 203: 25.00		UBLH2_SCHPO (7-325): 1.13e-114: 335: 38.77
+	Sp
		1357958 PSB6_SCHPO (3-205): 1.74e-64: 200: 25.46		UBLH2_SCHPO (7-325): 1.13e-114: 335: 38.77
+	Sp
		675394 PSB5_SCHPO (8-194): 6.56e-64: 200: 19.79		UBLH2_SCHPO (7-325): 1.13e-114: 335: 38.77
+	Sp
		1358177 PSB3_SCHPO (1-205): 1.1e-64: 199: 56.10		UBLH2_SCHPO (7-325): 1.13e-114: 335: 38.77
+	Hs
		832027 PSB3_HUMAN (1-205): 1.02e-71: 218: 100.00		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29
+	Hs
		656631 PSB6_HUMAN (7-200): 4.63e-70: 215: 22.68		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29
+	Hs
		594598 PSB1_HUMAN (2-205): 1.85e-65: 203: 23.94		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29
+	Hs
		637724 PSA2_HUMAN (8-205): 1.92e-64: 200: 14.85		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29
+	Hs
		656282 PSA5_HUMAN (8-203): 6.92e-64: 199: 12.20		BAP1_HUMAN (246-315): 2.11e-16: 82: 34.29