HitPredict

Interactor 1: PSB2 (P49721)
Proteasome subunit beta type-2 (Macropain subunit C7-I) (Multicatalytic endopeptidase complex subunit C7-I) (Proteasome component C7-I)
Gene: PSMB2

Interactor 2: PSMG2 (Q969U7)
Proteasome assembly chaperone 2 (PAC-2) (Hepatocellular carcinoma-susceptibility protein 3) (Tumor necrosis factor superfamily member 5-induced protein 1)
Gene: PSMG2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 201 Hs			1 264
+	Hs
		656071 PSB8_HUMAN (2-196): 1.71e-68: 211: 19.49		PSMG2_HUMAN (1-264): 8.69e-146: 410: 100.00
+	Hs
		656755 PSB5_HUMAN (2-197): 1.96e-66: 206: 17.86		PSMG2_HUMAN (1-264): 8.69e-146: 410: 100.00
+	Hs
		1282447 PSB7_HUMAN (3-199): 1.32e-64: 202: 19.80		PSMG2_HUMAN (1-264): 8.69e-146: 410: 100.00
+	Hs
		638173 PSA4_HUMAN (3-198): 5.76e-65: 202: 17.73		PSMG2_HUMAN (1-264): 8.69e-146: 410: 100.00
+	Hs
		637728 PSA2_HUMAN (4-197): 1.04e-64: 201: 17.86		PSMG2_HUMAN (1-264): 8.69e-146: 410: 100.00
+	Hs
		594603 PSB1_HUMAN (3-198): 2.07e-57: 182: 23.42		PSMG2_HUMAN (1-264): 8.69e-146: 410: 100.00
+	Dm
		1178959 Q7K148_DROME (2-198): 6.07e-66: 205: 22.34		Q9VEC2_DROME (1-264): 7.68e-111: 321: 25.09
+	Dm
		1364522 Q9VJJ0_DROME (1-195): 3.77e-66: 203: 51.28		Q9VEC2_DROME (1-264): 7.68e-111: 321: 25.09
+	Dm
		1364531 Q9W470_DROME (2-199): 3.44e-64: 202: 19.70		Q9VEC2_DROME (1-264): 7.68e-111: 321: 25.09
+	Dm
		1364528 Q9VUJ1_DROME (4-199): 3.12e-64: 201: 19.90		Q9VEC2_DROME (1-264): 7.68e-111: 321: 25.09
+	Dm
		771313 PSA2_DROME (4-197): 4.6e-64: 199: 18.88		Q9VEC2_DROME (1-264): 7.68e-111: 321: 25.09