Protein: CDH1
APC/C activator protein CDH1 (CDC20 homolog 1) (Homolog of CDC twenty 1)

Gene: CDH1
Organism: Saccharomyces cerevisiae S288C
Interactions: 98
UniProt ID: P53197

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005680 - anaphase-promoting complex
GO:0005737 - cytoplasm
GO:0010697 - negative regulation of mitotic spindle pole body separation
GO:0010997 - anaphase-promoting complex binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

758314

HSL1
Probable serine/threonine-protein kinase HSL1

14

11

Small-scale

0.764

High

364659

CDK1
Cyclin-dependent kinase 1

9

17

Small-scale

0.758

High

822230

SECU
Securin

12

1

Small-scale

0.757

High

667105

CG22
G2/mitotic-specific cyclin-2

11

20

Small-scale

0.756

High

918129

ACM1
APC/C-CDH1 modulator 1

9

2

Small-scale

0.756

High

597616

CDC23
Anaphase-promoting complex subunit CDC23

8

20

Small-scale

0.742

High

486787

CDC16
Anaphase-promoting complex subunit CDC16

6

20

Small-scale

0.729

High

792479

CDC27
Anaphase-promoting complex subunit CDC27

6

20

Small-scale

0.719

High

893279

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

4

20

Small-scale

0.689

High

918117

CDC14
Tyrosine-protein phosphatase CDC14

3

15

Small-scale

0.670

High

709884

BMH1
Protein BMH1

3

7

Small-scale

0.667

High

585719

UBC4
Ubiquitin-conjugating enzyme E2 4

3

12

Small-scale

0.655

High

718953

CGS5
S-phase entry cyclin-5

3

20

Small-scale

0.651

High

667144

CG23
G2/mitotic-specific cyclin-3

3

20

Small-scale

0.650

High

760309

BMH2
Protein BMH2

3

7

Small-scale

0.646

High

916906

APC10
Anaphase-promoting complex subunit DOC1

3

11

Small-scale

0.637

High

739990

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

2

12

Small-scale

0.634

High

670306

NAP1
Nucleosome assembly protein

2

7

Small-scale

0.611

High

810734

TCPB
T-complex protein 1 subunit beta

2

20

Small-scale

0.611

High

684635

CDC20
APC/C activator protein CDC20

2

17

Small-scale

0.595

High

918114

APC1
Anaphase-promoting complex subunit 1

2

10

Small-scale

0.595

High

844420

TCPH
T-complex protein 1 subunit eta

2

20

Small-scale

0.594

High

632433

CG12
G1/S-specific cyclin CLN2

2

20

Small-scale

0.584

High

805559

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

20

Small-scale

0.578

High

575045

CDC26
Anaphase-promoting complex subunit CDC26

2

1

Small-scale

0.571

High

918131

APC11
Anaphase-promoting complex subunit 11

2

8

Small-scale

0.571

High

918134

APC2
Anaphase-promoting complex subunit 2

2

20

Small-scale

0.571

High

915388

MSN5
Protein MSN5

1

17

Small-scale

0.552

High

918123

TOS4
Protein TOS4

1

0

Small-scale

0.549

High

827027

MND2
Anaphase-promoting complex subunit MND2

2

0

Small-scale

0.547

High

918122

APC4
Anaphase-promoting complex subunit 4

2

0

Small-scale

0.547

High

918126

APC5
Anaphase-promoting complex subunit 5

2

0

Small-scale

0.547

High

918130

APC9
Anaphase-promoting complex subunit 9

2

0

Small-scale

0.547

High

918133

SWM1
Anaphase-promoting complex subunit SWM1

2

0

Small-scale

0.547

High

626824

HSP60
Heat shock protein 60, mitochondrial

2

20

Small-scale

0.543

High

810994

TCPD
T-complex protein 1 subunit delta

2

20

Small-scale

0.543

High

740597

IME2
Meiosis induction protein kinase IME2/SME1

1

18

High-throughput

0.536

High

797276

YBY8
Uncharacterized protein YBR138C

1

0

Small-scale

0.529

High

918120

YHP1
Homeobox protein YHP1

1

2

Small-scale

0.527

High

640562

UBC1
Ubiquitin-conjugating enzyme E2 1

1

15

Small-scale

0.501

High

656552

KC11
Casein kinase I homolog 1

1

19

High-throughput

0.501

High

699420

CIN8
Kinesin-like protein CIN8

1

16

Small-scale

0.501

High

918125

SGO1
Shugoshin

1

1

Small-scale

0.501

High

918132

IQG1
Ras GTPase-activating-like protein IQG1

1

13

Small-scale

0.501

High

865014

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.500

High

810857

TCPG
T-complex protein 1 subunit gamma

1

20

High-throughput

0.489

High

918112

CDH1
APC/C activator protein CDH1

1

16

Small-scale

0.481

High

661211

SPO13
Meiosis-specific protein SPO13

1

0

Small-scale

0.480

High

918113

NRM1
Transcription factor NRM1

1

0

Small-scale

0.480

High

918127

NDD1
Nuclear division defective protein 1

1

0

Small-scale

0.480

High

394753

EF1A
Elongation factor 1-alpha

1

3

Small-scale

0.479

High

402063

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

8

Small-scale

0.479

High

453976

IF4E
Eukaryotic translation initiation factor 4E

1

3

Small-scale

0.479

High

590681

HSP26
Heat shock protein 26

1

1

Small-scale

0.479

High

639040

VPS1
Vacuolar protein sorting-associated protein 1

1

5

Small-scale

0.479

High

664452

MCM3
DNA replication licensing factor MCM3

1

11

Small-scale

0.479

High

678982

NOT1
General negative regulator of transcription subunit 1

1

1

Small-scale

0.479

High

734704

IMB3
Importin subunit beta-3

1

12

Small-scale

0.479

High

738410

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

4

Small-scale

0.479

High

764124

SPT21
Protein SPT21

1

1

High-throughput

0.479

High

796604

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

15

Small-scale

0.479

High

803152

ECM29
Proteasome component ECM29

1

14

Small-scale

0.479

High

815182

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

8

Small-scale

0.479

High

815827

BEM2
GTPase-activating protein BEM2/IPL2

1

9

Small-scale

0.479

High

817912

IMB4
Importin subunit beta-4

1

15

Small-scale

0.479

High

850627

SA155
SIT4-associating protein SAP155

1

1

Small-scale

0.479

High

917039

MCM6
DNA replication licensing factor MCM6

1

12

Small-scale

0.479

High

918115

MPS1
Serine/threonine-protein kinase MPS1

1

20

Small-scale

0.479

High

918116

UFD2
E4 ubiquitin-protein ligase UFD2

1

3

Small-scale

0.479

High

918121

PDS5
Sister chromatid cohesion protein PDS5

1

2

High-throughput

0.479

High

918128

NEW1
[NU+] prion formation protein 1

1

10

Small-scale

0.479

High

750049

PDR3
Transcription factor PDR3

1

0

Small-scale

0.460

High

625969

UBR1
E3 ubiquitin-protein ligase UBR1

1

0

Small-scale

0.458

High

813564

MET10
Sulfite reductase [NADPH] flavoprotein component

1

0

Small-scale

0.458

High

828302

MKT1
Post-transcriptional regulator MKT1

1

0

Small-scale

0.458

High

918118

FIN1
Filament protein FIN1

1

0

Small-scale

0.458

High

918119

DOP1
Protein DOP1

1

0

Small-scale

0.458

High

405116

LEU3
3-isopropylmalate dehydrogenase

1

7

High-throughput

0.457

High

555115

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.457

High

510668

HSP77
Import motor subunit, mitochondrial

1

20

High-throughput

0.445

High

524636

HSP71
Heat shock protein SSA1

1

20

High-throughput

0.445

High

545660

SSB1
Ribosome-associated molecular chaperone SSB1

1

20

High-throughput

0.445

High

819335

SSB2
Ribosome-associated molecular chaperone SSB2

1

20

High-throughput

0.445

High

824495

6P21
6-phosphofructo-2-kinase 1

1

2

High-throughput

0.445

High

864936

NOP9
Nucleolar protein 9

1

1

High-throughput

0.445

High

538346

PYC1
Pyruvate carboxylase 1

1

15

Small-scale

0.437

High

554716

YPK1
Serine/threonine-protein kinase YPK1

1

11

Small-scale

0.437

High

732174

COPG
Coatomer subunit gamma

1

11

Small-scale

0.437

High

816595

GEA2
ARF guanine-nucleotide exchange factor 2

1

2

Small-scale

0.437

High

836009

COPB
Coatomer subunit beta

1

8

Small-scale

0.437

High

874280

MON2
Protein MON2

1

2

Small-scale

0.437

High

918135

OSH2
Oxysterol-binding protein homolog 2

1

3

Small-scale

0.437

High

577182

SEC63
Protein translocation protein SEC63

1

12

High-throughput

0.407

High

918124

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

0

High-throughput

0.261

Low

817214

FIR1
Factor interacting with REF2

1

0

Small-scale

0.251

Low

673516

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

0

Small-scale

0.249

Low

733775

ACH1
Acetyl-CoA hydrolase

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025