Interactor 1: MCM3M (P49739)
Maternal DNA replication licensing factor mcm3 (EC 3.6.4.12) (Maternal minichromosome maintenance protein 3) (mMCM3) (xMCM3) (P1 homolog) (XRLF subunit beta) (p100)
Gene: mmcm3

Interactor 2: MCM5A (P55862)
DNA replication licensing factor mcm5-A (xMCM5-A) (EC 3.6.4.12) (CDC46 homolog A) (xCDC46-A) (CDC46p) (p92)
Gene: mcm5-a

Species: Xenopus laevis

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 9214647, 9214646
Identification Methods anti bait coimmunoprecipitation, chromatography technology
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~MCM, MCM~MCM_lid, MCM~MCM_N, MCM~MCM_OB, MCM_N~MCM_N, MCM_N~MCM_OB, MCM_OB~MCM_OB
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0000785 - chromatin
GO:0003697 - single-stranded DNA binding
GO:0005524 - ATP binding
GO:0006268 - DNA unwinding involved in DNA replication
and 6 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 807
Xl

1 735
+ Hs
+ Hs
+ Mm
+ Dm
+ Xl
+ Xl
+ Xl
+ Xl
+ Xl
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Dm
+ Dm
+ Dm
+ Sp
+ Ce

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Last updated: 15 Jul 2024