HitPredict

Interactor 1: EI2BB (P49770)
Translation initiation factor eIF2B subunit beta (S20I15) (S20III15) (eIF2B GDP-GTP exchange factor subunit beta)
Gene: EIF2B2

Interactor 2: NECT4 (Q96NY8)
Nectin-4 (Ig superfamily receptor LNIR) (Nectin cell adhesion molecule 4) (Poliovirus receptor-related protein 4) [Cleaved into: Processed poliovirus receptor-related protein 4]
Gene: NECTIN4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 351 Hs			1 510
+	Hs
		793625 EI2BB_HUMAN (1-351): 6.51e-152: 433: 100.00		DCC_HUMAN (29-498): 1.49e-42: 164: 15.05
+	Hs
		1298944 EI2BD_HUMAN (24-341): 2.15e-89: 279: 21.52		NECT4_HUMAN (1-510): 1.12e-99: 311: 100.00
+	Hs
		1051836 EI2BA_HUMAN (16-344): 4.96e-78: 243: 22.96		NECT4_HUMAN (1-510): 1.12e-99: 311: 100.00
+	Hs
		793665 EI2BD_HUMAN (24-341): 2.15e-89: 279: 21.52		DCC_HUMAN (29-498): 1.49e-42: 164: 15.05
+	Hs
		793639 EI2BA_HUMAN (16-344): 4.96e-78: 243: 22.96		DCC_HUMAN (29-498): 1.49e-42: 164: 15.05