HitPredict

Interactor 1: FHIT (P49789)
Bis(5'-adenosyl)-triphosphatase (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Adenosine 5'-monophosphoramidase FHIT) (EC 3.9.1.-) (Adenylylsulfatase) (EC 3.6.2.1) (Adenylylsulfate-ammonia adenylyltransferase) (EC 2.7.7.51) (Diadenosine 5',5'''-P1,P3-triphosphate hydrolase) (Dinucleosidetriphosphatase) (Fragile histidine triad protein)
Gene: FHIT

Interactor 2: FHIT (P49789)
Bis(5'-adenosyl)-triphosphatase (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Adenosine 5'-monophosphoramidase FHIT) (EC 3.9.1.-) (Adenylylsulfatase) (EC 3.6.2.1) (Adenylylsulfate-ammonia adenylyltransferase) (EC 2.7.7.51) (Diadenosine 5',5'''-P1,P3-triphosphate hydrolase) (Dinucleosidetriphosphatase) (Fragile histidine triad protein)
Gene: FHIT

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.978

The method score is based on:

Property Details
Experiments 25416956, 16189514, 27107012, 32296183, 24722188, 18077326, 31515488, unassigned1304, 9576908, 9261067
Identification Methods two hybrid, two hybrid array, barcode fusion genetics two hybrid, validated two hybrid, pull down, two hybrid prey pooling approach, x-ray crystallography, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HIT~HIT
Common GO terms GO:0000166 - nucleotide binding
GO:0001650 - fibrillar center
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
and 11 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 147
Hs

1 147
+ At
+ Sp
+ Sc
+ Hs
+ Hp
+ Hs
+ Ss
+ Mp
+ Sp
+ Sc
+ Hs
+ Ca
+ Cj
+ Ec
+ Zm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024