Protein: DCTN3
Dynactin subunit 3 (Dynactin complex subunit 22 kDa subunit) (p22)

Gene: DCTN3
Organism: Homo sapiens
Interactions: 120
UniProt ID: O75935

Gene Ontology (top 5):
GO:0000278 - mitotic cell cycle
GO:0000776 - kinetochore
GO:0005198 - structural molecule activity
GO:0005730 - nucleolus
GO:0005813 - centrosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

278609

DCTN2
Dynactin subunit 2

7

0

High-throughput

0.916

High

278611

DCTN1
Dynactin subunit 1

5

1

High-throughput

0.720

High

278591

CAZA2
F-actin-capping protein subunit alpha-2

4

1

High-throughput

0.699

High

278590

ACTY
Beta-centractin

3

3

High-throughput

0.667

High

278605

GPS2
G protein pathway suppressor 2

3

0

High-throughput

0.638

High

278597

ACTZ
Alpha-centractin

2

3

High-throughput

0.611

High

126666

DCTN6
Dynactin subunit 6

2

0

High-throughput

0.602

High

278592

CAPZB
F-actin-capping protein subunit beta

2

0

High-throughput

0.602

High

278635

AROS
Active regulator of SIRT1

2

0

High-throughput

0.602

High

278673

MS18A
Protein Mis18-alpha

2

0

High-throughput

0.602

High

278595

ATX1
Ataxin-1

2

0

High-throughput

0.593

High

278579

KLHL2
Kelch-like protein 2

2

0

High-throughput

0.585

High

278607

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

2

0

High-throughput

0.585

High

278618

CSPP1
Centrosome and spindle pole-associated protein 1

2

0

High-throughput

0.585

High

278577

KRT34
Keratin, type I cuticular Ha4

2

0

High-throughput

0.580

High

278624

ACTBL
Beta-actin-like protein 2

2

2

High-throughput

0.574

High

272833

KS6A4
Ribosomal protein S6 kinase alpha-4

1

1

High-throughput

0.536

High

278594

CAZA1
F-actin-capping protein subunit alpha-1

1

1

High-throughput

0.536

High

278598

ACTA
Actin, aortic smooth muscle

1

2

High-throughput

0.536

High

278600

ACTG
Actin, cytoplasmic 2

1

2

High-throughput

0.536

High

278613

KS6A2
Ribosomal protein S6 kinase alpha-2

1

1

High-throughput

0.536

High

278649

NACC2
Nucleus accumbens-associated protein 2

1

1

High-throughput

0.536

High

278656

DCTN5
Dynactin subunit 5

1

1

High-throughput

0.536

High

204468

ARK72
Aflatoxin B1 aldehyde reductase member 2

1

0

High-throughput

0.513

High

278576

RAD17
Cell cycle checkpoint protein RAD17

1

0

High-throughput

0.513

High

278578

UBP19
Ubiquitin carboxyl-terminal hydrolase 19

1

0

High-throughput

0.513

High

278581

SNP29
Synaptosomal-associated protein 29

1

0

High-throughput

0.513

High

278585

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.513

High

278586

CSK22
Casein kinase II subunit alpha'

1

0

High-throughput

0.513

High

278588

CLIP1
CAP-Gly domain-containing linker protein 1

1

0

High-throughput

0.513

High

278599

DYL1
Dynein light chain 1, cytoplasmic

1

0

High-throughput

0.513

High

278603

TF65
Transcription factor p65

1

0

High-throughput

0.513

High

278608

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

0

High-throughput

0.513

High

278610

RIN1
Ras and Rab interactor 1

1

0

High-throughput

0.513

High

278612

TRIPC
E3 ubiquitin-protein ligase TRIP12

1

0

High-throughput

0.513

High

278614

STIL
SCL-interrupting locus protein

1

0

High-throughput

0.513

High

278617

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.513

High

278622

RGL3
Ral guanine nucleotide dissociation stimulator-like 3

1

0

High-throughput

0.513

High

278632

SEP14
Septin-14

1

0

High-throughput

0.513

High

278634

CLAP1
CLIP-associating protein 1

1

0

High-throughput

0.513

High

278643

NEDD1
Protein NEDD1

1

0

High-throughput

0.513

High

278646

CTF18
Chromosome transmission fidelity protein 18 homolog

1

0

High-throughput

0.513

High

278648

SYMPK
Symplekin

1

0

High-throughput

0.513

High

278657

THUM3
tRNA

1

0

High-throughput

0.513

High

278661

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.513

High

278664

MARH7
E3 ubiquitin-protein ligase MARCHF7

1

0

High-throughput

0.513

High

278667

BIRC6
Baculoviral IAP repeat-containing protein 6

1

0

High-throughput

0.513

High

278676

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.513

High

278679

JIP3
C-Jun-amino-terminal kinase-interacting protein 3

1

0

High-throughput

0.513

High

278680

POMP
Proteasome maturation protein

1

0

High-throughput

0.513

High

278682

RRP44
Exosome complex exonuclease RRP44

1

0

High-throughput

0.513

High

278683

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

1

0

High-throughput

0.513

High

157846

KLF11
Krueppel-like factor 11

1

0

High-throughput

0.493

High

278593

GSK3B
Glycogen synthase kinase-3 beta

1

0

High-throughput

0.486

High

278639

NIN
Ninein

1

1

High-throughput

0.479

High

278653

SCLT1
Sodium channel and clathrin linker 1

1

1

High-throughput

0.479

High

278681

NINL
Ninein-like protein

1

1

High-throughput

0.479

High

122415

MEN1
Menin

1

0

High-throughput

0.458

High

159006

UB2L6
Ubiquitin/ISG15-conjugating enzyme E2 L6

1

0

High-throughput

0.458

High

160295

AURKA
Aurora kinase A

1

0

High-throughput

0.458

High

278596

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

278606

NMI
N-myc-interactor

1

0

High-throughput

0.458

High

278630

LMTK1
Serine/threonine-protein kinase LMTK1

1

0

High-throughput

0.458

High

278647

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

278675

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

278678

DCTN4
Dynactin subunit 4

1

0

High-throughput

0.458

High

278660

TRI55
Tripartite motif-containing protein 55

1

1

High-throughput

0.439

High

214006

SPOP
Speckle-type POZ protein

1

1

High-throughput

0.437

High

278631

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

278671

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

1

High-throughput

0.437

High

278637

ASPM
Abnormal spindle-like microcephaly-associated protein

1

0

Small-scale

0.426

High

278652

CI072
Guanine nucleotide exchange factor C9orf72

1

0

Small-scale

0.426

High

89954

D6R9G5
Kelch like family member 2

1

1

High-throughput

0.407

High

278583

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

2

0

High-throughput

0.328

High

278662

PDGFD
Platelet-derived growth factor D

2

0

High-throughput

0.328

High

278663

DB127
Beta-defensin 127

2

0

High-throughput

0.328

High

278587

C4BPB
C4b-binding protein beta chain

2

0

High-throughput

0.318

High

278668

CAH10
Carbonic anhydrase-related protein 10

2

0

High-throughput

0.318

High

278670

THAP1
THAP domain-containing protein 1

2

0

High-throughput

0.318

High

60542

VP37C
Vacuolar protein sorting-associated protein 37C

2

0

High-throughput

0.316

High

278601

PITX1
Pituitary homeobox 1

2

0

High-throughput

0.316

High

278616

PCH2
Pachytene checkpoint protein 2 homolog

2

0

High-throughput

0.316

High

278633

NUP54
Nucleoporin p54

2

0

High-throughput

0.316

High

278641

USBP1
Harmonin-binding protein USHBP1

2

0

High-throughput

0.316

High

64039

AQ12B
Aquaporin-12B

1

0

High-throughput

0.279

Low

278580

CXL14
C-X-C motif chemokine 14

1

0

High-throughput

0.279

Low

278582

CYTS
Cystatin-S

1

0

High-throughput

0.279

Low

278584

TSP1
Thrombospondin-1

1

0

High-throughput

0.279

Low

278602

FOXK2
Forkhead box protein K2

1

0

High-throughput

0.279

Low

278604

COASY
Bifunctional coenzyme A synthase

1

0

High-throughput

0.279

Low

278615

MED22
Mediator of RNA polymerase II transcription subunit 22

1

0

High-throughput

0.279

Low

278619

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

278620

EDRF1
Erythroid differentiation-related factor 1

1

0

High-throughput

0.279

Low

278621

INAVA
Innate immunity activator protein

1

0

High-throughput

0.279

Low

278625

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.279

Low

278627

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.279

Low

278628

N42L1
NEDD4-binding protein 2-like 1

1

0

High-throughput

0.279

Low

278629

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

0

High-throughput

0.279

Low

278636

I2BP1
Interferon regulatory factor 2-binding protein 1

1

0

High-throughput

0.279

Low

278640

LRA25
Leucine repeat adapter protein 25

1

0

High-throughput

0.279

Low

278642

PAF1
RNA polymerase II-associated factor 1 homolog

1

0

High-throughput

0.279

Low

278644

CC4L
C-C motif chemokine 4-like

1

0

High-throughput

0.279

Low

278645

ZN398
Zinc finger protein 398

1

0

High-throughput

0.279

Low

278650

PAUF
Pancreatic adenocarcinoma up-regulated factor

1

0

High-throughput

0.279

Low

278651

VCIP1
Deubiquitinating protein VCPIP1

1

0

High-throughput

0.279

Low

278654

RGPD5
RANBP2-like and GRIP domain-containing protein 5/6

1

0

High-throughput

0.279

Low

278655

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

0

High-throughput

0.279

Low

278659

SELO
Protein adenylyltransferase SelO, mitochondrial

1

0

High-throughput

0.279

Low

278666

RIC8A
Synembryn-A

1

0

High-throughput

0.279

Low

278669

ABCF3
ATP-binding cassette sub-family F member 3

1

0

High-throughput

0.279

Low

278658

NUP58
Nucleoporin p58/p45

1

0

High-throughput

0.268

Low

278623

DUS28
Dual specificity phosphatase 28

1

0

High-throughput

0.249

Low

278626

PHF19
PHD finger protein 19

1

0

High-throughput

0.249

Low

278665

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.249

Low

278672

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.249

Low

278674

RN181
E3 ubiquitin-protein ligase RNF181

1

0

High-throughput

0.249

Low

278677

DS13B
Dual specificity protein phosphatase 13B

1

0

High-throughput

0.249

Low

278589

PBX2
Pre-B-cell leukemia transcription factor 2

1

0

Small-scale

0.238

Low

239658

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.232

Low

278638

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024