HitPredict

Interactor 1: RBP2 (P49792)
E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) (p270)
Gene: RANBP2

Interactor 2: RBP2 (P49792)
E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) (p270)
Gene: RANBP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.757

The method score is based on:

Property Details
Experiments 16194093, 20936779
Identification Methods enzymatic study, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pro_isomerase~Pro_isomerase, Ran_BP1~Ran_BP1
Common GO terms GO:0001975 - response to amphetamine
GO:0003723 - RNA binding
GO:0005096 - GTPase activator activity
GO:0005635 - nuclear envelope
GO:0005642 - annulate lamellae
and 25 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 3224
Hs

1 3224
+ Hs
+ Ce
+ Zm
+ Hs
+ Hs
+ Sc
+ Sc
+ Zm
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024