HitPredict

Interactor 1: RGS3 (P49796)
Regulator of G-protein signaling 3 (RGP3) (RGS3)
Gene: RGS3

Interactor 2: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	11985497, 16160139, 20347994
Identification Methods	affinity chromatography technology, pull down, fluorescence polarization spectroscopy
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1198 Hs			1 245
+	Hs
		646729 RGS3_HUMAN (1-1198): 0: 953: 100.00		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		683208 RGS3_HUMAN (1-1198): 0: 953: 100.00		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Hs
		647296 SMUF1_HUMAN (151-667): 1.41e-77: 274: 17.83		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Rn
		910358 NEDD4_RAT (111-604): 8.72e-71: 257: 17.74		1433E_RAT (2-241): 9.9e-144: 403: 68.18
+	Hs
		566348 KPCA_HUMAN (124-271): 6.07e-71: 253: 30.87		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Mm
		808343 NEDD4_MOUSE (111-604): 1.15e-69: 253: 18.34		1433E_MOUSE (2-241): 9.9e-144: 403: 68.18
+	Rn
		933150 NEDD4_RAT (111-604): 8.72e-71: 257: 17.74		1433T_RAT (1-245): 8.98e-140: 393: 79.18
+	Hs
		566293 KPCA_HUMAN (124-271): 6.07e-71: 253: 30.87		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Hs
		397155 KPCG_HUMAN (81-272): 5.35e-62: 227: 31.61		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Rn
		716563 NEDD4_RAT (111-604): 8.72e-71: 257: 17.74		1433B_RAT (1-242): 2e-128: 364: 86.78
+	Mm
		808372 NEDD4_MOUSE (111-604): 1.15e-69: 253: 18.34		1433B_MOUSE (1-242): 3.77e-128: 364: 87.19
+	Rn
		905367 NEDD4_RAT (111-604): 8.72e-71: 257: 17.74		1433G_RAT (1-240): 2.37e-108: 314: 74.59
+	Rn
		935725 NEDD4_RAT (111-604): 8.72e-71: 257: 17.74		1433F_RAT (2-240): 1.16e-107: 312: 74.07
+	Hs
		566346 KPCA_HUMAN (124-271): 6.07e-71: 253: 30.87		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		408587 KPCB_HUMAN (124-271): 2.1e-67: 242: 30.87		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		397154 KPCG_HUMAN (81-272): 5.35e-62: 227: 31.61		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		397138 KPCG_HUMAN (81-272): 5.35e-62: 227: 31.61		1433S_HUMAN (1-237): 8.27e-104: 302: 71.97