HitPredict

Interactor 1: RGS3 (P49796)
Regulator of G-protein signaling 3 (RGP3) (RGS3)
Gene: RGS3

Interactor 2: EFNB1 (P98172)
Ephrin-B1 (EFL-3) (ELK ligand) (ELK-L) (EPH-related receptor tyrosine kinase ligand 2) (LERK-2) [Cleaved into: Ephrin-B1 C-terminal fragment (Ephrin-B1 CTF); Ephrin-B1 intracellular domain (Ephrin-B1 ICD)]
Gene: EFNB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1198 Hs			1 346
+	Hs
		834894 RGS3_HUMAN (1-1198): 0: 953: 100.00		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		834903 RGS3_HUMAN (1-1198): 0: 953: 100.00		EFNB3_HUMAN (33-346): 6.4e-107: 318: 41.28
+	Hs
		957942 SMUF1_HUMAN (151-667): 1.41e-77: 274: 17.83		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		957938 SMUF2_HUMAN (151-666): 3.45e-77: 272: 18.48		EFNB1_HUMAN (1-346): 0: 538: 100.00