HitPredict - High confidence protein-protein interactions

Interactor 1: TSC2 (P49816)
Tuberin (Tuberous sclerosis 2 protein homolog)
Gene: TSC2

Interactor 2: TSC1 (Q9Z136)
Hamartin (Tuberous sclerosis 1 protein homolog)
Gene: TSC1

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	12147258, 9809973
Identification Methods	biochemical, anti bait coimmunoprecipitation
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001843 - neural tube closure GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005765 - lysosomal membrane GO:0005829 - cytosol and 18 others more... GO:0008283 - cell population proliferation GO:0008285 - negative regulation of cell population proliferation GO:0009267 - cellular response to starvation GO:0014069 - postsynaptic density GO:0016020 - membrane GO:0016239 - positive regulation of macroautophagy GO:0016242 - negative regulation of macroautophagy GO:0030030 - cell projection organization GO:0030426 - growth cone GO:0032007 - negative regulation of TOR signaling GO:0033596 - TSC1-TSC2 complex GO:0042995 - cell projection GO:0045792 - negative regulation of cell size GO:0046323 - glucose import GO:0048471 - perinuclear region of cytoplasm GO:0051726 - regulation of cell cycle GO:0051879 - Hsp90 protein binding GO:1904262 - negative regulation of TORC1 signaling
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1	1809
Rn

1	1163

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024