Protein: 6PGD
6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44)

Gene: 6PGD, Pgd
Organism: Drosophila melanogaster
Interactions: 167
UniProt ID: P41572

Gene Ontology (top 5):
GO:0004616 - phosphogluconate dehydrogenase (decarboxylating) activity
GO:0005829 - cytosol
GO:0009051 - pentose-phosphate shunt, oxidative branch
GO:0019521 - D-gluconate metabolic process
GO:0042593 - glucose homeostasis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

578045

ENO
Enolase

2

2

High-throughput

0.571

High

835130

TRXR1
Thioredoxin reductase 1, mitochondrial

2

2

High-throughput

0.571

High

835220

Q9VTY2
Uncharacterized protein, isoform A

2

5

High-throughput

0.571

High

835230

CLIC
Chloride intracellular channel Clic

2

2

High-throughput

0.571

High

460001

ALF
Fructose-bisphosphate aldolase

2

0

High-throughput

0.547

High

835124

MOEH
Moesin/ezrin/radixin homolog 1

2

0

High-throughput

0.547

High

835151

Q8IRD3
Glutathione peroxidase

2

0

High-throughput

0.547

High

649010

ANX10
Annexin B10

2

1

High-throughput

0.521

High

762517

UCHL
Ubiquitin carboxyl-terminal hydrolase

2

1

High-throughput

0.521

High

835128

PDI
Protein disulfide-isomerase

2

1

High-throughput

0.521

High

835137

NLP
Nucleoplasmin-like protein

2

3

High-throughput

0.521

High

835166

Q9V3V2
peptidylprolyl isomerase

2

5

High-throughput

0.521

High

835181

Q9VEB1
Malate dehydrogenase, mitochondrial

2

1

High-throughput

0.521

High

835184

Q9VGK3
peptidylprolyl isomerase

2

5

High-throughput

0.521

High

835209

Q9VPX6
Adenylyl cyclase-associated protein

2

1

High-throughput

0.521

High

835219

Q9VSL2
Glutathione S transferase O3

2

1

High-throughput

0.521

High

835239

Q9W227
Peptidyl-prolyl cis-trans isomerase

2

1

High-throughput

0.521

High

835142

Q7JX87
1-Cys peroxiredoxin

1

1

High-throughput

0.479

High

835185

Q9VGM2
Fatty acid-binding protein, muscle

1

1

High-throughput

0.479

High

835193

PYRD1
Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1

1

1

High-throughput

0.464

High

52437

A1Z6X6
Lactoylglutathione lyase

1

0

High-throughput

0.458

High

47751

A0AQH0
Proteasome subunit beta

1

1

High-throughput

0.445

High

53978

A1Z892
1-Cys peroxiredoxin

1

1

High-throughput

0.445

High

121190

ALDR
Aldo-keto reductase 1B

1

5

High-throughput

0.445

High

556644

PSA1
Proteasome subunit alpha type-1

1

1

High-throughput

0.445

High

611468

PSA4
Proteasome subunit alpha type-4

1

1

High-throughput

0.445

High

652727

PSA71
Proteasome subunit alpha type-7-1

1

1

High-throughput

0.445

High

821815

PSA2
Proteasome subunit alpha type-2

1

1

High-throughput

0.445

High

822033

PSB1
Proteasome subunit beta type-1

1

3

High-throughput

0.445

High

835125

FKB12
Peptidyl-prolyl cis-trans isomerase Fkbp12

1

5

High-throughput

0.445

High

835132

PGK
Phosphoglycerate kinase

1

1

High-throughput

0.445

High

835138

SAHH
Adenosylhomocysteinase

1

1

High-throughput

0.445

High

835141

Q7JVH6
LD24696p

1

5

High-throughput

0.445

High

835144

Q7K148
Proteasome subunit beta

1

1

High-throughput

0.445

High

835146

TERA
Transitional endoplasmic reticulum ATPase TER94

1

4

High-throughput

0.445

High

835147

Q7KN85
ATP-citrate synthase

1

1

High-throughput

0.445

High

835149

Q8INK3
Fatty acid-binding protein, muscle

1

1

High-throughput

0.445

High

835150

Q8IQZ7
FI19014p1

1

1

High-throughput

0.445

High

835152

Q8MT58
Carnosine dipeptidase 2, isoform A

1

1

High-throughput

0.445

High

835168

THIO2
Thioredoxin-2

1

1

High-throughput

0.445

High

835170

PSA3
Proteasome subunit alpha type-3

1

1

High-throughput

0.445

High

835182

FLNA
Filamin-A

1

1

High-throughput

0.445

High

835186

Q9VH81
protein-serine/threonine phosphatase

1

2

High-throughput

0.445

High

835189

Q9VHN7
transketolase

1

1

High-throughput

0.445

High

835191

Q9VHX4
LD24679p

1

5

High-throughput

0.445

High

835196

Q9VKZ8
Ubiquitin carboxyl-terminal hydrolase

1

1

High-throughput

0.445

High

835203

AK200
A-kinase anchor protein 200

1

1

High-throughput

0.445

High

835207

PSB4
Proteasome subunit beta type-4

1

5

High-throughput

0.445

High

835212

Q9VQL1
serine--tRNA ligase

1

1

High-throughput

0.445

High

835215

Q9VRL1
GEO06356p1

1

1

High-throughput

0.445

High

835222

Q9VUC1
Hsc70Cb, isoform A

1

1

High-throughput

0.445

High

835248

PSB3
Proteasome subunit beta type-3

1

3

High-throughput

0.445

High

835251

Q9Y112
BcDNA.GH10614

1

5

High-throughput

0.445

High

835247

Q9W5E6
Histone H4 transcription factor, isoform C

1

1

High-throughput

0.439

High

55136

A1Z933
GEO02273p1

1

0

High-throughput

0.438

High

120751

M9PE30
Transgelin

1

1

High-throughput

0.437

High

835205

Q9VM16
LP02603p

1

1

High-throughput

0.437

High

835231

Q9VYR1
Regucalcin

1

1

High-throughput

0.437

High

357261

O97428
Ciboulot, isoform A

1

0

High-throughput

0.426

High

458084

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

0

High-throughput

0.426

High

726313

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

835126

RIR2
Ribonucleoside-diphosphate reductase subunit M2

1

0

High-throughput

0.426

High

835127

DOD
Putative peptidyl-prolyl cis-trans isomerase dodo

1

0

High-throughput

0.426

High

835134

Q0E993
Valine--tRNA ligase

1

0

High-throughput

0.426

High

835143

Q7K0E6
Aspartate--tRNA ligase, cytoplasmic

1

0

High-throughput

0.426

High

835156

Q8T0L3
E1 ubiquitin-activating enzyme

1

0

High-throughput

0.426

High

835161

JUPIT
Microtubule-associated protein Jupiter

1

0

High-throughput

0.426

High

835162

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.426

High

835171

TPP2
Tripeptidyl-peptidase 2

1

0

High-throughput

0.426

High

835173

Q9VAC1
GM14349p

1

0

High-throughput

0.426

High

835175

Q9VAN7
Phosphoglycerate mutase

1

0

High-throughput

0.426

High

835178

Q9VCK6
LD34157p

1

0

High-throughput

0.426

High

835179

Q9VD02
GH14779p

1

0

High-throughput

0.426

High

835183

Q9VG31
Malic enzyme

1

0

High-throughput

0.426

High

835187

TEBPH
Cytosolic Prostaglandin E synthase

1

0

High-throughput

0.426

High

835188

Q9VHL2
T-complex protein 1 subunit eta

1

0

High-throughput

0.426

High

835190

DPP3
Dipeptidyl peptidase 3

1

0

High-throughput

0.426

High

835192

Q9VIE8
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.426

High

835195

Q9VKW5
Prolyl endopeptidase

1

0

High-throughput

0.426

High

835197

EF1D
Probable elongation factor 1-delta

1

0

High-throughput

0.426

High

835202

Q9VLB7
Rab GDP dissociation inhibitor

1

0

High-throughput

0.426

High

835206

Q9VN44
FI07923p

1

0

High-throughput

0.426

High

835218

Q9VSI6
Isocitrate dehydrogenase [NADP]

1

0

High-throughput

0.426

High

835227

Q9VW59
Rho GDP-dissociation inhibitor 3

1

0

High-throughput

0.426

High

835237

SND1
Staphylococcal nuclease domain-containing protein 1

1

0

High-throughput

0.426

High

835241

Q9W3F6
Bleomycin hydrolase

1

0

High-throughput

0.426

High

305134

O77260
EG:115C2.6 protein

1

1

High-throughput

0.417

High

57528

A1ZB71
Glutathione S transferase E6

1

1

High-throughput

0.407

High

197737

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

1

High-throughput

0.407

High

234737

O46067
Hypoxia up-regulated protein 1

1

1

High-throughput

0.407

High

426636

HP1
Heterochromatin protein 1

1

5

High-throughput

0.407

High

561767

MODU
DNA-binding protein modulo

1

1

High-throughput

0.407

High

648862

ANXB9
Annexin B9

1

1

High-throughput

0.407

High

835133

HMGD
High mobility group protein D

1

4

High-throughput

0.407

High

835135

Q0KHZ6
Electron transfer flavoprotein subunit beta

1

1

High-throughput

0.407

High

835136

VATA2
V-type proton ATPase catalytic subunit A isoform 2

1

1

High-throughput

0.407

High

835139

Q76NR6
Regucalcin

1

1

High-throughput

0.407

High

835154

OLA1
Obg-like ATPase 1

1

1

High-throughput

0.407

High

835155

Q8SYG3
E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.407

High

835158

SUCA
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial

1

1

High-throughput

0.407

High

835169

PDIA6
Protein disulfide-isomerase A6 homolog

1

2

High-throughput

0.407

High

835172

Q9V9U3
LD45254p

1

1

High-throughput

0.407

High

835174

Q9VAC4
GEO09167p1

1

3

High-throughput

0.407

High

835176

Q9VAY2
Heat shock protein 83

1

2

High-throughput

0.407

High

835177

Q9VB96
Uncharacterized protein, isoform A

1

2

High-throughput

0.407

High

835180

Q9VD29
small monomeric GTPase

1

1

High-throughput

0.407

High

835198

Q9VL68
Enoyl-CoA delta isomerase 1, mitochondrial

1

1

High-throughput

0.407

High

835200

FKB59
FK506-binding protein 59

1

4

High-throughput

0.407

High

835201

Q9VL89
Methionine aminopeptidase 2

1

1

High-throughput

0.407

High

835204

SYAC
Alanine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.407

High

835208

Q9VPN5
Stress-induced-phosphoprotein 1

1

2

High-throughput

0.407

High

835214

Q9VRD6
NTF2-related export protein

1

1

High-throughput

0.407

High

835216

Q9VRP2
Uncharacterized protein, isoform A

1

1

High-throughput

0.407

High

835226

Q9VVL7
Dihydrolipoyl dehydrogenase

1

1

High-throughput

0.407

High

835229

DHB4
Peroxisomal multifunctional enzyme type 2

1

1

High-throughput

0.407

High

835232

TXND5
Thioredoxin domain-containing protein 5 homolog

1

2

High-throughput

0.407

High

835233

Q9VZI1
Transgelin

1

1

High-throughput

0.407

High

835236

Q9W0H8
Reticulocalbin-3

1

1

High-throughput

0.407

High

835244

CISY
Probable citrate synthase, mitochondrial

1

1

High-throughput

0.407

High

835246

NSUN2
tRNA

1

1

High-throughput

0.407

High

195007

O16043
Anon1A4

2

0

High-throughput

0.298

High

356307

O97102
Small ubiquitin-related modifier

2

0

High-throughput

0.298

High

357473

INO1
Inositol-3-phosphate synthase

2

0

High-throughput

0.298

High

476912

NDKA
Nucleoside diphosphate kinase

2

0

High-throughput

0.298

High

609367

PCNA
Proliferating cell nuclear antigen

2

0

High-throughput

0.298

High

712324

CALR
Calreticulin

2

0

High-throughput

0.298

High

835153

Q8STA5
Histidine triad nucleotide binding protein 1, isoform A

2

0

High-throughput

0.298

High

835163

SH3BG
SH3 domain-binding glutamic acid-rich protein homolog

2

0

High-throughput

0.298

High

835167

Q9V3V9
Endonuclease G inhibitor, isoform A

2

0

High-throughput

0.298

High

835238

Q9W1H7
Putative homeodomain protein

1

0

High-throughput

0.249

Low

57751

A1ZB77
Uncharacterized protein, isoform J

1

0

High-throughput

0.232

Low

86460

B9EQV3
Endoplasmic reticulum transmembrane protein

1

0

High-throughput

0.232

Low

145953

UGDH
UDP-glucose 6-dehydrogenase

1

0

High-throughput

0.232

Low

234545

VINC
Vinculin

1

0

High-throughput

0.232

Low

305637

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.232

Low

356535

O97121
cystathionine gamma-lyase

1

0

High-throughput

0.232

Low

632940

GLNA1
Glutamine synthetase 1, mitochondrial

1

0

High-throughput

0.232

Low

682713

PROF
Profilin

1

0

High-throughput

0.232

Low

835129

VATE
V-type proton ATPase subunit E

1

0

High-throughput

0.232

Low

835131

SODM
Superoxide dismutase [Mn], mitochondrial

1

0

High-throughput

0.232

Low

835140

Q7JR58
Probable enoyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.232

Low

835145

Q7K2K2
FI04612p

1

0

High-throughput

0.232

Low

835148

Q7KTW5
Inositol-1-monophosphatase

1

0

High-throughput

0.232

Low

835157

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.232

Low

835159

FAXC
Failed axon connections

1

0

High-throughput

0.232

Low

835160

IF5A
Eukaryotic translation initiation factor 5A

1

0

High-throughput

0.232

Low

835164

Q9V3D8
GH27579p

1

0

High-throughput

0.232

Low

835165

Q9V3I1
Deoxyuridine 5'-triphosphate nucleotidohydrolase

1

0

High-throughput

0.232

Low

835194

Q9VKB0
threonine--tRNA ligase

1

0

High-throughput

0.232

Low

835199

Q9VL70
HL08109p

1

0

High-throughput

0.232

Low

835210

Q9VQ61
Aspartate aminotransferase

1

0

High-throughput

0.232

Low

835211

BACC
Bacchus

1

0

High-throughput

0.232

Low

835213

Q9VQL7
Fatty acid synthase

1

0

High-throughput

0.232

Low

835217

Q9VSC5
GM09977p

1

0

High-throughput

0.232

Low

835221

Q9VU35
10 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.232

Low

835223

GARS
Glycine--tRNA ligase

1

0

High-throughput

0.232

Low

835224

Y9705
Cold shock domain-containing protein CG9705

1

0

High-throughput

0.232

Low

835225

Q9VVC5
2-oxoglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.232

Low

835228

Q9VWQ7
Coactosin-like protein

1

0

High-throughput

0.232

Low

835234

Q9VZY0
LD45195p

1

0

High-throughput

0.232

Low

835235

Q9W0E4
Aminopeptidase

1

0

High-throughput

0.232

Low

835240

Q9W2M4
Farnesoic acid O-methyl transferase domain-containing protein

1

0

High-throughput

0.232

Low

835242

Q9W3X6
fumarate hydratase

1

0

High-throughput

0.232

Low

835243

Q9W3Y3
Calcyclin-binding protein

1

0

High-throughput

0.232

Low

835245

Q9W457
Serine hydroxymethyltransferase

1

0

High-throughput

0.232

Low

835249

Q9XZ57
Eb1, isoform E

1

0

High-throughput

0.232

Low

835250

PURA
Adenylosuccinate synthetase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025