HitPredict

Interactor 1: GSK3A (P49840)
Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)
Gene: GSK3A

Interactor 2: SRSF3 (P84103)
Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Splicing factor, arginine/serine-rich 3)
Gene: SRSF3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27684187
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 483 Hs			1 164
+	Hs
		835345 GSK3A_HUMAN (16-483): 7.48e-155: 450: 100.00		SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65
+	Hs
		835356 GSK3A_HUMAN (16-483): 7.48e-155: 450: 100.00		PABP4_HUMAN (5-91): 1.61e-21: 91.9: 26.09
+	Hs
		516418 GSK3A_HUMAN (16-483): 7.48e-155: 450: 100.00		PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77
+	Hs
		625466 CDK2_HUMAN (116-413): 1.52e-147: 425: 32.03		SRSF7_HUMAN (9-106): 1.02e-30: 112: 67.35
+	Hs
		516362 CDK2_HUMAN (116-413): 1.52e-147: 425: 32.03		PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77
+	Hs
		516419 GSK3B_HUMAN (65-471): 1.58e-145: 424: 76.41		PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77
+	Hs
		625590 CDK2_HUMAN (116-413): 1.52e-147: 425: 32.03		RBM4_HUMAN (11-88): 3.45e-18: 81.9: 28.21
+	Zm
		11307 A0A1D6FC67_MAIZE (49-451): 3e-150: 436: 57.28		C0P488_MAIZE (7-95): 1.07e-12: 66.5: 14.58
+	Dm
		576505 SGG_DROME (68-456): 1.03e-137: 408: 73.15		SRSF7_DROME (7-95): 4.01e-18: 80.1: 64.84
+	Dm
		576290 SGG_DROME (68-456): 1.03e-137: 408: 73.15		SRR55_DROME (11-89): 1.88e-16: 77: 46.84
+	At
		621700 CDKA1_ARATH (116-406): 5.55e-134: 390: 32.78		RB45A_ARATH (8-109): 9.99e-19: 83.4: 16.67
+	At
		1340936 MPK10_ARATH (122-429): 3.46e-53: 185: 34.28		RB47C_ARATH (8-99): 6.55e-16: 75.7: 18.37