HitPredict

Interactor 1: GSK3B (P49841)
Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)
Gene: GSK3B

Interactor 2: LIPB1 (Q86W92)
Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2)
Gene: PPFIBP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	36779422, 36736316
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~SAM_1
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 420 Hs			1 1011
+	Hs
		835436 GSK3A_HUMAN (21-420): 1.87e-147: 429: 77.75		LIPB1_HUMAN (1-1011): 7.51e-135: 433: 100.00
+	Hs
		835913 GSK3B_HUMAN (1-408): 1.15e-162: 465: 100.00		ANS1A_HUMAN (502-904): 1.42e-45: 180: 15.23
+	Dm
		576751 SGG_DROME (1-393): 8.87e-144: 421: 77.16		Q9VU88_DROME (388-928): 2.17e-53: 200: 32.05
+	Hs
		835475 GSK3A_HUMAN (21-420): 1.87e-147: 429: 77.75		ANS1A_HUMAN (502-904): 1.42e-45: 180: 15.23
+	Hs
		724714 GSK3B_HUMAN (1-408): 1.15e-162: 465: 100.00		MYH9_HUMAN (2-781): 5.58e-30: 131: 7.15
+	Hs
		625176 CDK2_HUMAN (53-350): 8.22e-147: 420: 31.70		MYH9_HUMAN (2-781): 5.58e-30: 131: 7.15
+	Hs
		625177 CDK2_HUMAN (53-350): 8.22e-147: 420: 31.70		MYH10_HUMAN (2-784): 3.65e-29: 128: 8.24
+	Hs
		835712 GSK3B_HUMAN (1-408): 1.15e-162: 465: 100.00		LIPA1_HUMAN (1-598): 1.48e-09: 64.2: 9.82
+	Hs
		528401 CDK2_HUMAN (53-350): 8.22e-147: 420: 31.70		MYH8_HUMAN (2-529): 9.87e-20: 97.6: 9.65
+	Hs
		960128 CDK3_HUMAN (53-348): 5.47e-137: 396: 31.91		MYH2_HUMAN (16-806): 8.98e-26: 117: 8.00
+	Hs
		528368 CDK3_HUMAN (53-348): 5.47e-137: 396: 31.91		MYH6_HUMAN (2-794): 8.99e-25: 114: 9.50
+	Hs
		522542 CDK3_HUMAN (53-348): 5.47e-137: 396: 31.91		MYH1_HUMAN (185-793): 7.46e-20: 98: 9.05
+	Hs
		528405 CDK3_HUMAN (53-348): 5.47e-137: 396: 31.91		MYH8_HUMAN (2-529): 9.87e-20: 97.6: 9.65
+	Hs
		835352 GSK3A_HUMAN (21-420): 1.87e-147: 429: 77.75		LIPA1_HUMAN (1-598): 1.48e-09: 64.2: 9.82
+	Dm
		576667 SGG_DROME (1-393): 8.87e-144: 421: 77.16		Q9VM93_DROME (56-568): 1.18e-10: 68.1: 7.13
+	Hs
		522604 CDK3_HUMAN (53-348): 5.47e-137: 396: 31.91		MYH7_HUMAN (4-426): 2.63e-13: 76.8: 10.58
+	Hs
		960129 CDK3_HUMAN (53-348): 5.47e-137: 396: 31.91		MYH13_HUMAN (1-409): 8.9e-13: 74.9: 9.76
+	Hs
		502908 CDK3_HUMAN (53-348): 5.47e-137: 396: 31.91		MYH3_HUMAN (18-342): 1.75e-11: 70.7: 7.69
+	Hs
		724717 CDK7_HUMAN (56-374): 2.6e-51: 177: 36.61		MYH9_HUMAN (2-781): 5.58e-30: 131: 7.15
+	Hs
		518840 CDK7_HUMAN (56-374): 2.6e-51: 177: 36.61		TPR_HUMAN (70-620): 8.21e-09: 62.3: 10.65