Interactor 1: GSK3B (P49841)
Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)
Gene: GSK3B

Interactor 2: AXIN2 (Q9Y2T1)
Axin-2 (Axin-like protein) (Axil) (Axis inhibition protein 2) (Conductin)
Gene: AXIN2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.977

The method score is based on:

Property Details
Experiments 33961781, 10966653, 12183362, 36572560, 29568061, 30824926, 32707033, 36736316, 23602568, 23455922, unassigned1655
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, pull down, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~RGS
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 9 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 420
Hs

1 843
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Ce
+ Dm

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Last updated: 15 Jul 2024