HitPredict

Interactor 1: TAF6 (P49848)
Transcription initiation factor TFIID subunit 6 (RNA polymerase II TBP-associated factor subunit E) (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII70) (Transcription initiation factor TFIID 80 kDa subunit) (TAF(II)80) (TAFII-80) (TAFII80)
Gene: TAF6

Interactor 2: TAF8 (Q7Z7C8)
Transcription initiation factor TFIID subunit 8 (Protein taube nuss) (TBP-associated factor 43 kDa) (TBP-associated factor 8) (Transcription initiation factor TFIID 43 kDa subunit) (TAFII-43) (TAFII43) (hTAFII43)
Gene: TAF8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.737

The method score is based on:

Property	Details
Experiments	26186194, 28514442, 33961781, 17375202, 14580349, 23292512
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005669 - transcription factor TFIID complex GO:0006367 - transcription initiation at RNA polymerase II promoter GO:0016251 - RNA polymerase II general transcription initiation factor activity and 4 others more... GO:0042789 - mRNA transcription by RNA polymerase II GO:0046982 - protein heterodimerization activity GO:0051123 - RNA polymerase II preinitiation complex assembly GO:0060261 - positive regulation of transcription initiation by RNA polymerase II
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	677
Hs

1	310

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024