HitPredict

Interactor 1: CDN1C (P49918)
Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57Kip2)
Gene: CDKN1C

Interactor 2: SKP2 (Q13309)
S-phase kinase-associated protein 2 (Cyclin-A/CDK2-associated protein p45) (F-box protein Skp2) (F-box/LRR-repeat protein 1) (p45skp2)
Gene: SKP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	12925736, 19686743
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 316 Hs			1 424
+	Hs
		758216 CDN1A_HUMAN (17-148): 7.59e-31: 115: 29.20		SKP2_HUMAN (1-424): 3e-94: 291: 100.00
+	Mm
		803851 CDN1B_MOUSE (9-201): 1.47e-28: 110: 23.83		SKP2_MOUSE (1-424): 1.32e-92: 287: 86.32
+	Hs
		804120 CDN1B_HUMAN (9-201): 9.76e-25: 100: 21.76		SKP2_HUMAN (1-424): 3e-94: 291: 100.00
+	Xl
		991526 Q91646_XENLA (26-155): 1.89e-17: 81.3: 28.46		Q075B2_XENLA (1-418): 1.73e-75: 243: 55.74
+	Hs
		836907 CDN1C_HUMAN (1-316): 3.21e-37: 137: 100.00		FXL12_HUMAN (99-385): 2.56e-21: 96: 23.89
+	Hs
		758347 CDN1A_HUMAN (17-148): 7.59e-31: 115: 29.20		FXL12_HUMAN (99-385): 2.56e-21: 96: 23.89