HitPredict

Interactor 1: LAP2B (P42167)
Lamina-associated polypeptide 2, isoforms beta/gamma (Thymopoietin, isoforms beta/gamma) (TP beta/gamma) (Thymopoietin-related peptide isoforms beta/gamma) (TPRP isoforms beta/gamma) [Cleaved into: Thymopoietin (TP) (Splenin); Thymopentin (TP5)]
Gene: TMPO

Interactor 2: LMNB2 (Q03252)
Lamin-B2
Gene: LMNB2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.642

Property	Details
Experiments	34079125, 9490046, 37071682
Identification Methods	proximity labelling technology, two hybrid, cross-linking study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope GO:0031965 - nuclear membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 620
+	Rn
		1000490 LAP2_RAT (1-454): 0: 630: 90.53		LMNB1_RAT (16-620): 3.13e-59: 210: 55.21
+	Hs
		385525 LAP2B_HUMAN (1-454): 0: 612: 100.00		LMNA_HUMAN (24-614): 1.1e-59: 212: 51.95
+	Hs
		634336 LAP2B_HUMAN (1-454): 0: 612: 100.00		LMNB1_HUMAN (16-620): 3.73e-59: 209: 56.03
+	Hs
		474531 LAP2B_HUMAN (1-454): 0: 612: 100.00		VIME_HUMAN (42-404): 6.19e-32: 130: 30.58
+	Hs
		385524 LAP2A_HUMAN (1-186): 3.1e-85: 277: 100.00		LMNA_HUMAN (24-614): 1.1e-59: 212: 51.95
+	Dr
		74837 Q503J3_DANRE (173-391): 8.22e-57: 193: 29.13		B3DKC5_DANRE (21-606): 1.53e-61: 217: 51.53
+	Dr
		74865 Q6DHI6_DANRE (1-213): 1.16e-43: 156: 29.15		B3DKC5_DANRE (21-606): 1.53e-61: 217: 51.53
+	Dr
		74847 Q5RGX2_DANRE (173-442): 3.09e-40: 149: 27.47		B3DKC5_DANRE (21-606): 1.53e-61: 217: 51.53