HitPredict

Interactor 1: MEOX2 (P50222)
Homeobox protein MOX-2 (Growth arrest-specific homeobox) (Mesenchyme homeobox 2)
Gene: MEOX2

Interactor 2: HMBX1 (Q6NT76)
Homeobox-containing protein 1 (Homeobox telomere-binding protein 1) (Telomere-associated homeobox-containing protein 1)
Gene: HMBOX1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Homeodomain~Homeodomain
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0043565 - sequence-specific DNA binding GO:1990837 - sequence-specific double-stranded DNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 304 Hs			1 420
+	Hs
		1151072 Q6FHY5_HUMAN (1-304): 1.09e-56: 186: 98.36		HMBX1_HUMAN (1-420): 3.22e-126: 373: 100.00
+	Hs
		620236 MEOX2_HUMAN (1-304): 2.38e-58: 190: 100.00		PAX3_HUMAN (75-410): 7.3e-73: 238: 17.92
+	Mm
		623694 MEOX2_MOUSE (1-304): 1.12e-55: 184: 96.71		PAX3_MOUSE (75-410): 1.97e-73: 239: 17.92
+	Mm
		623693 MEOX1_MOUSE (4-270): 2.46e-32: 121: 37.73		PAX3_MOUSE (75-410): 1.97e-73: 239: 17.92
+	Mm
		192281 ALX4_MOUSE (43-303): 1.39e-30: 120: 21.27		PAX3_MOUSE (75-410): 1.97e-73: 239: 17.92
+	Ce
		106229 MEC3_CAEEL (31-264): 1.53e-33: 126: 18.68		VAB3_CAEEL (70-418): 2.34e-66: 220: 15.04
+	Hs
		550483 MEOX2_HUMAN (1-304): 2.38e-58: 190: 100.00		PAX1_HUMAN (45-265): 2.08e-33: 133: 13.66
+	Ce
		447576 MEC3_CAEEL (31-264): 1.53e-33: 126: 18.68		HMBX1_CAEEL (22-418): 1.99e-57: 196: 25.06
+	Dm
		447432 UBX_DROME (40-248): 2.12e-30: 120: 24.88		GSBN_DROME (56-381): 4.04e-58: 198: 15.16
+	Mm
		447437 MEOX2_MOUSE (1-304): 1.12e-55: 184: 96.71		PAX1_MOUSE (45-265): 3.66e-33: 131: 12.78
+	Mm
		607522 EMX1_MOUSE (64-260): 6.15e-33: 123: 26.50		HNF1A_MOUSE (21-416): 3.56e-51: 183: 18.36
+	Ce
		105793 MEC3_CAEEL (31-264): 1.53e-33: 126: 18.68		PAX3H_CAEEL (75-376): 1.1e-51: 177: 13.92
+	Hs
		447229 HXB5_HUMAN (108-262): 1.13e-35: 131: 32.75		NKX21_HUMAN (115-382): 2.58e-34: 132: 11.36
+	Hs
		656400 PIT1_HUMAN (1-252): 5.17e-36: 132: 15.81		PITX1_HUMAN (237-389): 3.48e-32: 125: 24.84
+	Mm
		447436 MEOX1_MOUSE (4-270): 2.46e-32: 121: 37.73		PAX1_MOUSE (45-265): 3.66e-33: 131: 12.78
+	Hs
		174008 SHOX_HUMAN (166-246): 5.81e-32: 121: 35.80		SHOX_HUMAN (183-375): 2.06e-33: 128: 18.27
+	Dm
		950100 UBX_DROME (40-248): 2.12e-30: 120: 24.88		Q9W1H7_DROME (252-353): 1.79e-32: 124: 22.55
+	Dm
		620032 UBX_DROME (40-248): 2.12e-30: 120: 24.88		POXM_DROME (73-255): 7.54e-31: 123: 16.23
+	Mm
		192276 ALX4_MOUSE (43-303): 1.39e-30: 120: 21.27		RX_MOUSE (210-368): 1.13e-30: 122: 21.25
+	Dm
		949988 UBX_DROME (40-248): 2.12e-30: 120: 24.88		AL_DROME (233-376): 2.75e-30: 122: 21.53