HitPredict

Interactor 1: CRIP1 (P50238)
Cysteine-rich protein 1 (CRP-1) (Cysteine-rich heart protein) (CRHP) (hCRHP) (Cysteine-rich intestinal protein) (CRIP)
Gene: CRIP1

Interactor 2: SH3G3 (Q99963)
Endophilin-A3 (EEN-B2) (Endophilin-3) (SH3 domain protein 2C) (SH3 domain-containing GRB2-like protein 3)
Gene: SH3GL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	16169070
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 77 Hs			1 347
+	Hs
		1052265 MICA1_HUMAN (4-55): 7.68e-19: 80.4: 35.19		SRC8_HUMAN (7-343): 2.64e-50: 177: 14.49
+	Hs
		823393 PAXI_HUMAN (4-61): 4.8e-13: 64: 31.03		SRC8_HUMAN (7-343): 2.64e-50: 177: 14.49
+	Hs
		1256285 LIMA1_HUMAN (2-65): 1.27e-21: 88.3: 31.25		SH3R3_HUMAN (282-341): 8.78e-13: 71.3: 37.50
+	Hs
		924925 LIMA1_HUMAN (2-65): 1.27e-21: 88.3: 31.25		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		299005 LIMA1_HUMAN (2-65): 1.27e-21: 88.3: 31.25		SRBS2_HUMAN (291-344): 2.01e-10: 64.3: 48.15
+	Hs
		924720 MICA1_HUMAN (4-55): 7.68e-19: 80.4: 35.19		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		597760 CSRP1_HUMAN (3-69): 1.27e-18: 76.9: 44.78		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		823484 PAXI_HUMAN (4-61): 4.8e-13: 64: 31.03		SRBS1_HUMAN (169-342): 1.13e-13: 74.1: 17.65
+	Mm
		1113253 PAXI_MOUSE (4-61): 4.27e-13: 64: 31.03		SRBS2_MOUSE (243-342): 8.22e-12: 68.5: 20.59
+	Hs
		823431 PAXI_HUMAN (4-61): 4.8e-13: 64: 31.03		SH3R1_HUMAN (271-339): 2.43e-11: 66.8: 20.83
+	Hs
		924889 PDLI7_HUMAN (3-58): 2.48e-13: 64.8: 22.81		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38
+	Hs
		823365 PAXI_HUMAN (4-61): 4.8e-13: 64: 31.03		GRB2_HUMAN (290-346): 9.93e-12: 65.5: 41.38