HitPredict

Interactor 1: MAD1 (P50538)
Max dimerization protein 1 (Max dimerizer 1) (Protein MAD)
Gene: Mxd1

Interactor 2: SIN3B (Q62141)
Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b)
Gene: SIN3B

Species: Mus musculus

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.42	0.60	0.506

Property	Details
Experiments	7889570
Identification Methods	coimmunoprecipitation, two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 227 Mm			1 1098
+	Mm
		840233 MXI1_MOUSE (7-213): 2.36e-53: 173: 56.00		SIN3B_MOUSE (1-1098): 0: 1366: 100.00
+	Mm
		139907 MNT_MOUSE (34-176): 2.97e-36: 136: 26.80		SIN3B_MOUSE (1-1098): 0: 1366: 100.00
+	Hs
		257755 MXI1_HUMAN (7-213): 1.47e-56: 181: 55.11		SIN3B_HUMAN (14-1098): 0: 1304: 86.89
+	Hs
		257734 MYC_HUMAN (27-138): 3.46e-31: 120: 22.73		SIN3B_HUMAN (14-1098): 0: 1304: 86.89
+	Rn
		61827 MYC_RAT (27-140): 3.14e-32: 123: 22.39		A6K9M6_RAT (1-280): 3.92e-95: 306: 96.79
+	Mm
		840195 MAD1_MOUSE (1-227): 4.18e-80: 241: 100.00		SIN3A_MOUSE (71-357): 1.33e-12: 74.5: 14.49
+	Hs
		983439 MAD1_HUMAN (1-227): 4.05e-67: 207: 84.28		SIN3A_HUMAN (71-357): 1.1e-12: 74.9: 14.49
+	Hs
		840222 MXI1_HUMAN (7-213): 1.47e-56: 181: 55.11		SIN3A_HUMAN (71-357): 1.1e-12: 74.9: 14.49
+	Mm
		840232 MXI1_MOUSE (7-213): 2.36e-53: 173: 56.00		SIN3A_MOUSE (71-357): 1.33e-12: 74.5: 14.49
+	Mm
		1141057 Q91VN7_MOUSE (21-207): 4.04e-47: 156: 51.03		SIN3A_MOUSE (71-357): 1.33e-12: 74.5: 14.49
+	Dm
		1137188 X2JDM5_DROME (42-154): 4.64e-28: 113: 24.56		Q5U0Y0_DROME (134-264): 5.22e-23: 108: 41.79
+	Ce
		60879 MXL3_CAEEL (53-125): 4.65e-18: 81.4: 24.66		SIN3_CAEEL (4-156): 7.01e-31: 134: 31.82
+	Hs
		1302436 MAD3_HUMAN (8-169): 3.01e-40: 138: 49.13		SIN3A_HUMAN (71-357): 1.1e-12: 74.9: 14.49
+	Mm
		139906 MNT_MOUSE (34-176): 2.97e-36: 136: 26.80		SIN3A_MOUSE (71-357): 1.33e-12: 74.5: 14.49
+	Hs
		1302431 MNT_HUMAN (34-176): 1.19e-34: 131: 26.14		SIN3A_HUMAN (71-357): 1.1e-12: 74.9: 14.49
+	Hs
		347665 MYC_HUMAN (27-138): 3.46e-31: 120: 22.73		SIN3A_HUMAN (71-357): 1.1e-12: 74.9: 14.49
+	Hs
		898177 MAX_HUMAN (45-154): 7.39e-20: 84.5: 21.82		SIN3A_HUMAN (71-357): 1.1e-12: 74.9: 14.49